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Early 1990s research conducted by Peter Koopman, John Gubbay, Nigel Vivian, Peter Goodfellow, and Robin Lovell-Badge, showed that chromosomally…
Y ChromosomeTestisEmbryosChromosomesSex ChromosomesIn humans, sex determination is the process that determines the biological sex of an offspring and, as a result, the sexual characteristics that they…
Sex DeterminationGenetic sex determinationIntersex peopleDiscrimination against intersex peopleStevens, N. M. (Nettie Maria), 1861-1912The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex ChromosomesIn 2009, Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers developed the technology of mitochondrial gene replacement therapy to…
TechnologymonkeysGurdon, J. B. (John Bertrand)Briggs, Robert, -1983King, Thomas J. (Thomas Joseph), 1921-2000In the late 1980s, Peter Goodfellow in London, UK led a team of researchers who showed that the SRY gene in humans codes a protein that causes testes…
TestisY ChromosomeEmbryosChromosomesSex ChromosomesThe Y-chromosome is one of a pair of chromosomes that determine the genetic sex of individuals in mammals, some insects, and some plants. In the…
Y ChromosomeSex ChromosomesEmbryosDNAChromosomesShoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial DiseasesAmong other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblastsEdmund Beecher Wilson contributed to cell biology, the study of cells, in the US during the end of the nineteenth and the beginning of the twentieth…
EmbryologyCellsCytologyHeredityEvolutionAs of 2022, Trisomy 21 is the most common type of trisomy, or a condition where the person has three instead of the normal two copies of one of the…
Genetic DisordersGenetic disorders in childrenGenetic disorders in pregnancyGenetic disorders--DiagnosisDown syndrome