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In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenesThe Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genesIn 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental BiologyEdmund Beecher Wilson contributed to cell biology, the study of cells, in the US during the end of the nineteenth and the beginning of the twentieth…
EmbryologyCellsCytologyHeredityEvolutionThe Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulationConrad Hal Waddington's "Experiments on Embryonic Induction III," published in 1934 in the Journal of Experimental Biology, describes the discovery…
Waddington, C. H. (Conrad Hal), 1905-1975EmbryosCell differentiationEmbryologyChickens--EmbryosThe epigenetic landscape is a concept representing embryonic development. It was proposed by Conrad Hal Waddington to illustrate the various…
Waddington, C. H. (Conrad Hal), 1905-1975EpigeneticsCell differentiationEmbryologyDevelopmental BiologyAmong other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblastsMesoderm is one of the three germ layers, groups of cells that interact early during the embryonic life of animals and from which organs and tissues…
MesodermGastrulationCell differentiationCellsTissuesEctoderm is one of three germ layers--groups of cells that coalesce early during the embryonic life of all animals except maybe sponges, and from…
EmbryosEmbryologyGastrulationCellsTissues