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Francois Jacob studied in
bacteria and bacteriophages at the Institut Pasteur in Paris, France,
in the second half of the twentieth century. In 1965, Jacob won the
Nobel Prize in Physiology or Medicine with Andre M. Lwoff and
Jacques L. Monod for their work on the genetic control of enzyme
synthesis. Jacob studied how genes control and regulate metabolic
enzymes in the bacterium Escherichia
coli (E. coli) and in lysogenic
bacterial systems. He contributed to theories of transcriptional gene
Keith Henry Stockman Campbell studied embryo growth and cell differentiation during the twentieth and twenty-first centuries in the UK. In 1995, Campbell and his scientific team used cells grown and differentiated in a laboratory to clone sheep for the first time. They named these two sheep Megan and Morag. Campbell and his team also cloned a sheep from adult cells in 1996, which they named Dolly. Dolly was the first mammal cloned from specialized adult (somatic) cells with the technique of somatic cell nuclear transfer (SCNT).
James William Kitching collected and studied fossils of dinosaurs and early humans in the twentieth century. He worked at the Bernard Price Institute for Paleontological Research in South Africa. During the fifty-three years he worked at the institute, Kitching spent eighteen of those in the field uncovering fossils. Kitching recovered fossils of early human ancestors, later called Australopithecines, as well as fossils of dinosaurs and ancient mammals. When he died in 2003, the Bernard Price Institute housed one of the largest fossil collections in the southern hemisphere.
"The Spandrels of San Marco and the Panglossian Paradigm: A Critique of the Adaptationist Programme" (1979), by Stephen J. Gould and Richard C. Lewontin
The Spandrels of San Marco and the Panglossian Paradigm:
A Critique of the Adaptationist Programme, hereafter called
The Spandrels, is an article written by Stephen J. Gould and
Richard C. Lewontin published in the Proceedings of the Royal
Society of London in 1979. The paper emphasizes issues with
what the two authors call adaptationism or the adaptationist
programme as a framework to explain how species and traits evolved. The paper
is one in a series of works in which Gould emphasized the
At the turn of the twentieth century, Edmund B. Wilson
performed experiments to show where germinal
matter was located in molluscs. At Columbia University in New York City,
New York, Wilson studied what causes cells to differentiate during
development. In 1904 he conducted his experiments on molluscs, and he modified the
theory about the location of germinal matter in the succeeding years. Wilson and others modified the
theory of germinal localization to accommodate results that showed
A Treatise on the Theory and Practice of Midwifery is a three volume collection of patient accounts that William Smellie published from 1752 to 1764. Smellie, a physician and instructor in obstetrics in Great Britain, published these compilations to share his expertise in reproductive medicine, while also providing his students and colleagues with a source of reference in their own medical practices. Smellie wrote these books to shift obstetrics from a discipline practiced by midwives with limited medical training to one practiced in a medical context by physicians.
The copper intrauterine device, or IUD, is a long-term, reversible contraceptive first introduced by Howard Tatum and Jamie Zipper in 1967. Health care providers place an IUD inside a woman’s uterus to prevent pregnancy. Copper IUDs are typically made of T-shaped plastic with some portion covered with exposed copper. Prior to the invention of the first IUDs, women had few long-term options for safe and reliable birth control. Those options mostly consisted of barrier methods and the oral birth control pill, which were only effective if used correctly and consistently.
The Pfeffer Zelle (Pfeffer Cell Apparatus), invented by Wilhelm Pfeffer in 1877, measured the minimum pressure needed to prevent a pure solvent from passing into a solution across a semi-permeable membrane, called osmotic pressure. The apparatus provided Pfeffer with a way to quantitatively measure osmotic pressure. Pfeffer devised the apparatus in the 1870s at the University of Basel in Basel, Switzerland, and he described the Pfeffer Cell Apparatus in his 1877 book Osmotische Untersuchungen: Studien Zur Zellmechanik (Osmotic Investigations: Studies on Cell Mechanics).
Equilibrium Density Gradient Centrifugation in Cesium Chloride Solutions Developed by Matthew Meselson and Franklin Stahl
Matthew Meselson, Franklin Stahl, and Jerome Vinograd, developed cesium chloride, or CsCl, density gradient centrifugation in the 1950s at the California Institute of Technology, or Caltech, in Pasadena, California. Density gradient centrifugation enables scientists to separate substances based on size, shape, and density. Meselson and Stahl invented a specific type of density gradient centrifugation, called isopycnic centrifugation that used a solution of cesium chloride to separate DNA molecules based on density alone.
"MicroSort, developed in 1990 by the Genetics and IVF Institute, is a form of pre-conception sex selection technology for humans. Laboratories located around the world use MicroSort technology to help couples increase their chances of conceiving a child of their desired sex. MicroSort separates male sperm cells based on which sex chromosome they contain, which results in separated semen samples that contain a higher percentage of sperm cells that carry the same sex chromosome.
“Invasive and Non-invasive Methods for the Diagnosis of Endometriosis” (2010), by Albert L. Hsu, Izabella Khachikyan, and Pamela Stratton
In 2010, Albert L. Hsu, Izebella Khchikyan, and Pamela Stratton published “Invasive and Non-invasive Methods for the Diagnosis of Endometriosis,” henceforth “Methods for the Diagnosis of Endometriosis,” in Clinical Obstetrics and Gynecology. In the article, the authors describe how specific types of endometriotic lesions appear in the body and evaluate five methods for diagnosing endometriosis. Endometriosis is the growth of endometrium, the tissue that normally lines the inside of the uterus, outside of the uterus.
The Report of the Committee of Inquiry into Human Fertilisation and Embryology (1984), by Mary Warnock and the Committee of Inquiry into Human Fertilisation and Embryology
The Report of the Committee of Inquiry
into Human Fertilisation and Embryology, commonly called the Warnock
Report after the chair of the committee Mary Warnock, is the 1984
publication of a UK governmental inquiry into the social impacts of
infertility treatment and embryological research. The birth of Louise
Brown in 1978 in Oldham, UK, sparked debate about reproductive and
embryological technologies. Brown was conceived through in vitro
fertilization (IVF), a process of fertilization that occurs outside of
"Altruism and the Origin of the Worker Caste" from The Ants (1990), by Bert Hölldobler and Edward Osborne Wilson
In 'Altruism and the Origin of the Worker Caste,' Bert Hölldobler and Edward Osborne Wilson explore the evolutionary origins of worker ants. 'Altruism and the Origin of the Worker Caste' is the fourth chapter of Hölldobler and Wilson's book, The Ants, which was published by The Belknap Press of Harvard University in Cambridge, Massachusetts, in 1990. In 'Altruism and the Origin of the Worker Caste,' Hölldobler and Wilson evaluate various explanations for how a non-reproductive caste of ant evolved.
Alec John Jeffreys created a process called DNA fingerprinting in the UK during the twentieth century. For DNA fingerprinting, technicians identify a person as the source of a biological sample by comparing the genetic information contained in the person's DNA to the DNA contained in the sample. Jeffreys developed the technique in the 1980s while at the University of Leicester in Leicester, UK. Jeffreys's technique had immediate applications. In forensic science, DNA fingerprinting enabled police to identify suspects of crimes based on their genetic identities.
Eugen Steinach researched sex hormones and their effects on mammals in the late nineteenth and early twentieth centuries in Europe. He experimented on rats by removing their testicles and implanting them elsewhere in their bodies, and he found that the testes interstitial cells produce male sex hormones. He developed the Steinach Rejuvenation Procedure, which he claimed could rejuvenate men by increasing their production of sex hormones. Steinach’s work on female sex hormones and on ovarian extracts led to the development of the first standardized injectable estrogen.
Stanley Alan Plotkin developed vaccines in the United States during the mid to late twentieth century. Plotkin began his research career at the Wistar Institute in Philadelphia, Pennsylvania, where he studied the rubella virus. In pregnant women, the rubella virus caused congenital rubella syndrome in the fetus, which led to various malformations and birth defects. Using WI-38 cells, a line of cells that originated from tissues of aborted fetuses, Plotkin successfully created RA27/3, a weakened strain of the rubella virus, which he then used to develop a rubella vaccine.
Written, produced, and directed by Toby Mcdonald, the 2005 National Geographic Channel film In the Womb uses the most recent technology to provide an intricate glimpse into the prenatal world. The technologies used, which include advanced photography, computer graphics, and 4-D ultrasound imaging, help to realistically illustrate the process of development and to answer questions about the rarely seen development of a human being.
Breast augmentation involves the use of implants or fat tissue to increase patient breast size. As of 2019, breast augmentation is the most popular surgical cosmetic procedure in the United States, with annual patient numbers increasing by 41 percent since the year 2000. Since the first documented breast augmentation by surgeon Vincenz Czerny in 1895, and later the invention of the silicone breast implant in 1963, surgeons have developed the procedure into its own specialized field of surgery, creating various operating techniques for different results.
Homology is a central concept of comparative and evolutionary biology, referring to the presence of the same bodily parts (e.g., morphological structures) in different species. The existence of homologies is explained by common ancestry, and according to modern definitions of homology, two structures in different species are homologous if they are derived from the same structure in the common ancestor.
Format: Essays and Theses