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Karl Wilhelm Theodor Richard von Hertwig (1850-1937)

Karl Wilhelm Theodor Richard von Hertwig is an important figure in the history of embryology for his contributions of artificial hybridization of sea urchin eggs and the formulation of his coelom theory. He was born 23 September 1850 in Friedelberg, Germany, to Elise Trapp and Carl Hertwig. Richard and his older brother Oscar began their studies at Jena under the direction of Ernst Haeckel from 1868 to 1871. In 1872 Hertwig became a lecturer in zoology at Jena while Oscar lectured in anatomy and embryology.

Format: Articles

Subject: People

Chorionic Villus Sampling

Chorionic villus sampling (CVS) is a test used for prenatal diagnosis. Safe to perform at an earlier stage in pregnancy than amniocentesis, CVS is another invasive prenatal diagnostic test that can be performed as early as ten weeks after the woman's last menstrual cycle. While this test does carry some risks, it is generally very effective at predicting heritable diseases during or soon after the embryonic stage of development.

Format: Articles

Subject: Technologies

Nicolaas Hartsoeker (1656-1725)

Nicolaas Hartsoeker, a Dutch astronomer, optics manufacturer, and naturalist, was born 26 March 1656 in Gouda, Netherlands, and died 10 December 1725. His mother was Anna van der Mey and his father was Christiaan Hartsoeker, a prominent evangelical minister. His major contribution to embryology was his observations of human sperm cells, which he claimed to be the first to see under a microscope. His sketch of the homunculus, a tiny preformed human he believed to exist in the head of spermatazoa, is his lasting scientific legacy in the field of embryology.

Format: Articles

Subject: People

Antoni van Leeuwenhoek (1632-1723)

Antoni van Leeuwenhoek was born in Delft, the Netherlands, on 24 October 1632 to Margriet Jacobsdochter van den Berch and Philips Thooniszoon, both of whom were middle-class artisans. He attended grammar school in Warmond, and then temporarily moved to Benthuizen to live with relatives. Eventually Leeuwenhoek left for Amsterdam to work as a cloth merchant's apprentice. Returning to Delft, he married Barbara de Mey on 29 July 1654, and worked as a shopkeeper. The marriage resulted in five children, only one of whom, Maria, outlived Leeuwenhoek.

Format: Articles

Subject: People

In re Marriage of Witten (2003)

In re Marriage of Witten, decided by the Iowa Supreme Court in 2003, held that neither Tamera nor Arthur (Trip) Witten could use or destroy several cryopreserved preembryos created during their marriage using in vitro fertilization (IVF), unless the former couple could reach a mutual agreement. Tamera and Trip Witten, unable to conceive conventionally during their marriage, had attempted to start a family together using IVF at the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska.

Format: Articles

Subject: Legal

Congenital Rubella Syndrome (CRS)

Congenital rubella syndrome (CRS) can occur in children whose mothers contracted the rubella virus, sometimes called German measles, during pregnancy. Depending on the gestational period when the mother contracts rubella, an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. The most severe effects of the virus on fetal development occur when the mother contracts rubella between conception and the first trimester.

Format: Articles

Subject: Disorders

Clomiphene Citrate

Clomiphene citrate, more commonly known by its brand names Clomid and Serophene, is a medication prescribed to women to stimulate ovulation in order to treat infertility. It stimulates ovulation in women who do not ovulate or ovulate irregularly. This drug was created by Dr. Frank Palopoli in 1956 while he worked for Merrell Company. It first successfully induced ovulation in women in 1961 and was approved by the Federal and Drug Administration (FDA) in 1967.

Format: Articles

Subject: Technologies

Marcello Malpighi (1646-1694)

Marcello Malpighi studied chick embryos with microscopes in Italy during the seventeenth century. Trained as a medical doctor, he was among the first scientists to use the microscope to examine embryos at very early stages. Malpighi described early structures in chick embryos, and later scientists used his descriptions to help develop the theory of preformationism.

Format: Articles

Subject: People

A. Z. v. B. Z. (2000)

In A.Z. v. B.Z. (2000), the Supreme Judicial Court of Massachusetts in Boston, Massachusetts, affirmed a lower courtÕs decision, ruling that contracts that require a party to become a parent against his or her will are unenforceable and contrary to public policy. The case centered around A.Z. and B.Z., a divorced couple who had previously used in vitro fertilization (IVF) to start a family together during their marriage and had several preembryos cryopreserved as part of the process.

Format: Articles

Subject: Legal

In the Matter of the Marriage of Dahl and Angle (2008)

In the 2008 court case In the Matter of the Marriage of Dahl and Angle, the Court of Appeals of Oregon upheld a written in vitro fertilization (IVF) consent form signed by Laura and Darrell Angle, who had each contributed their genetic material to the creation of several preembryos during their marriage. Its decision followed the general framework for resolving such disputes provided by the Supreme Court of Tennessee in Davis v. Davis in 1992, which was subsequently followed by many courts across the US.

Format: Articles

Subject: Legal

"Hybrids and Chimeras: A Consultation on the Ethical and Social Implications of Creating Human/Animal Embryos in Research" (2007), by the HFEA

To educate its citizens about research into chimeras made from human and non-human animal cells, the United Kingdom's Human Fertilisation Embryology Authority published the consultation piece Hybrids and Chimeras: A Consultation on the Ethical and Social Implications of Creating Human/Animal Embryos in Research, in 2007.

Format: Articles

Subject: Publications

Human Fertilisation and Embryology Act (1990)

The Human Fertilisation and Embryology Act 1990 established the legal framework that governs infertility treatment, medical services ancillary to infertility treatment such as embryo storage, and all human embryological research performed in the UK. The law also defines a legal concept of the parent of a child conceived with assisted reproductive technologies.

Format: Articles

Subject: Legal, Reproduction, Ethics

The Silent Scream (1984), by Bernard Nathanson, Crusade for Life, and American Portrait Films

The Silent Scream is an anti-abortion film released in 1984 by American Portrait Films, then based in Brunswick, Ohio. The film was created and narrated by Bernard Nathanson, an obstetrician and gynecologist from New York, and it was produced by Crusade for Life, an evangelical anti-abortion organization. In the video, Nathanson narrates ultrasound footage of an abortion of a twelve-week-old fetus, claiming that the fetus opened its mouth in what Nathanson calls a silent scream during the procedure.

Format: Articles

Subject: Outreach, Reproduction

Organic Seed Growers and Trade Association's suit against Monsanto, 2012 and 2013

In March 2011 the Organic Seed Growers and Trade Association and around sixty agricultural organizations (OSGATA et al.) filed a suit against Monsanto Company and Monsanto Technology L.L.C., collectively called Monsanto. The hearings for Organic Seed Growers and Trade Association (OSGATA) et al. v. Monsanto (2012) took place at the United States District Court for the Southern District of New York in Manhattan, New York. The district court's Judge Naomi Reice Buchwald dismissed OSGATA's suit.

Format: Articles

Subject: Legal

Francesco Redi (1626-1698)

Francesco Redi, son of Florentine physician Cecilia de' Ghinci and Gregorio Redi, was born in Arezzo, Italy, on 18 February 1626. He studied philosophy and medicine at the University of Pisa, graduating on 1 May 1647. A year later, Redi moved to Florence and registered at the Collegio Medico. There he served at the Medici Court as both the head physician and superintendent of the ducal pharmacy and foundry. Redi was also a member of the Accademia del Cimento, which flourished from 1657-1667. It was during this decade that Redi produced his most important works.

Format: Articles

Subject: People

Oviraptor philoceratops Dinosaurs

Oviraptor philoceratops was a small bird-like dinosaur that lived about seventy-five million years ago, during the late Cretaceous period. In 1923, George Olsen of the American Museum of Natural History (AMNH) in New York City, New York, discovered the first Oviraptor fossilized skeleton on top of a dinosaur egg nest in the Gobi Desert, Mongolia. Because of the close proximity of dinosaur and nest, when Henry Fairfield Osborn president of the AMNH published on the discovery, he assumed that the Oviraptor had died attempting to steal the eggs.

Format: Articles

Subject: Organisms

A Treatise on the Theory and Practice of Midwifery, (1752-1764) by William Smellie

A Treatise on the Theory and Practice of Midwifery is a three volume collection of patient accounts that William Smellie published from 1752 to 1764. Smellie, a physician and instructor in obstetrics in Great Britain, published these compilations to share his expertise in reproductive medicine, while also providing his students and colleagues with a source of reference in their own medical practices. Smellie wrote these books to shift obstetrics from a discipline practiced by midwives with limited medical training to one practiced in a medical context by physicians.

Format: Articles

“Miscarriage of Medicine: The Growth of Catholic Hospitals and the Threat to Reproductive Health Care” (2013), by Lois Uttley, Sheila Reynertson, Larraine Kenny, and Louise Melling

In 2013, Lois Uttley, Sheila Reynertson, Larraine Kenny, and Louise Melling published “Miscarriage of Medicine: The Growth of Catholic Hospitals and the Threat to Reproductive Health Care,” in which they analyzed the growth of Catholic hospitals in the United States from 2001 to 2011 and the impact those hospitals had on reproductive health care. In the US, Catholic hospitals are required to abide by the US Catholic Church's Ethical Guidelines for Health Care Providers, also called the Directives.

Format: Articles

Subject: Publications

“Delayed Breastfeeding Initiation Increases Risk of Neonatal Mortality” (2006), by Karen Edmond Charles Zandoh, Maria Quigley, Seeba Amenga-Etego, Seth Oqusi-Agyei, and Betty Kirkwood

In March 2006, scientists from Ghana and the UK Karen Edmond, Charles Zandoh, Maria Quigley, Seeba Amenga-Etego, Seth Oqusi-Agyei, and Betty Kirkwood published their findings that early, consistent breastfeeding habits for mothers in Ghana resulted in better survival outcomes for their infants. The authors communicated those results in the paper “Delayed Breastfeeding Initiation Increases Risk of Neonatal Mortality,” or “Delayed Breastfeeding,” published in The American Academy of Pediatrics.

Format: Articles

Subject: Publications

“Misericordia et Misera” Section 12 (2016) by Pope Francis of the Catholic Church

Misericordia et Misera (Mercy with Misery) was a letter written by Pope Francis and published in Rome, Italy, on 20 November 2016. Through the letter, Pope Francis gives priests the ability to grant forgiveness for abortion. Before Pope Francis’s letter, priests had some ability to grant forgiveness for the Catholic sin of abortion, but bishops had to grant that ability to the priests individually. Prior to the letter, the official rules of the Catholic Church did not state that priests could forgive abortion-related sins.

Format: Articles

Subject: Publications, Religion

Carol Downer (1933– )

Carol Downer was a reproductive health and abortion rights activist in the twentieth and twenty-first centuries in the US and other countries. During the late 1960s, many women reported knowing little about female anatomy and receiving little information from their physicians. Downer advocated for women’s reproductive anatomy education and encouraged women to not rely on the intervention of a medical doctor for all reproductive issues.

Format: Articles

The Sex Side of Life (1919) by Mary Ware Dennett

Mary Ware Dennett, an activist in the US for birth control and sex education in the early twentieth century, wrote an educational pamphlet in 1915 called “The Sex Side of Life, and it was published in 1919. The pamphlet defined the functions of the sex organs, emphasized the role of love and pleasure in sex, and described other sexual processes of the body not usually discussed openly.

Format: Articles

Subject: Publications

“Improving Women’s Health”: Section 3509 of the Affordable Care Act of 2010

In 2010, US Congress enacted section 3509 of the Patient Protection and Affordable Care Act or ACA, to target issues relating to women’s health. The ACA, signed into law by US President Barack Obama, aimed to increase people’s access to high-quality healthcare in the United States.

Format: Articles

Subject: Legal

“Consensus on the Current Management of Endometriosis” (2013), by Neil P. Johnson and Lone Hummelshoj

“Consensus on the Current Management of Endometriosis”, henceforth “Consensus”, was written by the World Endometriosis Society, or WES, president Neil P. Johnson and chief executive Lone Hummelshoj and published in 2013 in Human Reproduction. “Consensus” makes recommendations about managing endometriosis for women and healthcare professionals. Endometriosis is a condition where endometrium, the tissue that usually lines the uterus, grows outside of the uterus and is characterized by painful periods, heavy menstrual bleeding, and infertility.

Format: Articles

Subject: Publications