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Better Babies Contests in the United States (1908–1916)

Better babies contests were competitions held in state fairs throughout the US during the early twentieth century in which babies between the ages of 6 and 48 months were judged for their health. In 1908, social activist Mary de Garmo established and held the first better babies contest at the Louisiana State Fair in Shreveport, Louisiana. The contests, mirroring theories established in the US’s eugenics movement of the twentieth century, aimed to establish standards for judging infant health.

Format: Articles

Subject: Outreach

Henry Morgentaler (1923-2013)

Henry Morgentaler was a physician who performed abortions, acted as a reproductive rights activist, and advocated for legal access to abortions in Canada during the twentieth century. In 1969, he opened his first abortion clinic in Canada and participated in the legal/court case of R v. Morgentaler (1988), which led Canada to decriminalize abortion. Morgentaler helped establish legal access to abortions for women in Canada and advocated for the protection of women's reproductive choices under the law.

Format: Articles

Subject: People

CRISPR Acquired Resistance Against Viruses (2007)

In 2007, Philippe Horvath and his colleagues explained how bacteria protect themselves against viruses at Danisco, a Danish food company, in Dangé-Saint-Romain, France. Horvath and his team worked to improve the lifespan of bacteria cultures for manufacturing yogurt and ice cream. Specifically, they focused on bacteria’s resistance to bacteriophages, or viruses that infect bacteria. Horvath and his colleagues found that the bacteria used to culture yogurt, Streptococcus thermophilus, has an adaptive immune system that can target specific viruses that have previously infected the bacteria.

Format: Articles

Subject: Experiments

Burwell v. Hobby Lobby (2014)

In the 2014 case Burwell v. Hobby Lobby, the US Supreme Court ruled that the contraceptive mandate promulgated under the Patient Protection and Affordable Care Act violated privately held, for-profit corporations’ right to religious freedom. The contraception mandate, issued in 2012 by the US Department of Health and Human Services, required that employer-provided health insurance plans offer their beneficiaries certain contraceptive methods free of charge.

Format: Articles

Subject: Legal, Reproduction

Ian Donald (1910–1987)

Ian Donald was an obstetrician who developed the technology and therapy of ultrasound diagnostics during the twentieth century in Europe. Ultrasound is a medical diagnostic technique that uses sound waves to produce images of the inside of the body. During the early 1900s, physicians had no way to see inside a woman’s uterus during pregnancy. Donald developed the first method of scanning human internal anatomy in real time, which enabled doctors to diagnose potentially fatal tumors and cysts.

Format: Articles

Subject: People

Kangaroo Mother Care

Physician researchers Edgar Rey Sanabria and Héctor Martínez-Gómez developed the Kangaroo Mother Program in Bogotá, Colombia, in 1979, as an alternative to conventional incubator treatment for low birth weight infants. As of 2018, low birth weight and its associated complications are the leading causes of infant death, especially in developing and underdeveloped countries where access to technology and skilled healthcare providers is limited. Kangaroo Mother Care is a simple and low cost method for treating low birth weight infants.

Format: Articles

Subject: Technologies

Dennis Lo (1963- )

Dennis Lo, also called Yuk Ming Dennis Lo, is a
professor at the Chinese University of Hong Kong in Hong Kong,
China. In 1997, Lo discovered fetal DNA in maternal
plasma, which is the liquid component of a pregnant woman's
blood. By 2002, Lo distinguished the DNA differences between pregnant women
and their fetuses, enabling scientists to identify fetal DNA in pregnant
women's blood. Lo used his discoveries to develop several
non-invasive and prenatal genetic tests, including tests for blood

Format: Articles

Subject: People, Reproduction

Wolbachia

Bacteria of the genus Wolbachia are
bacteria that live within the cells of their hosts. They infect a
wide range of arthropods (insects, arachnids, and crustaceans) and
some nematodes (parasitic roundworms). Scientists estimate that
Wolbachia exist in between seventeen percent and seventy-six percent of
arthropods and nematodes. The frequency of the bacteria makes them
one of the most widespread parasites. In general, they are divided
into five groups, from A to E, depending of the species of their

Format: Articles

Subject: Organisms

Where Are My Children? (1916)

Where Are My Children? is an anti-abortion silent film released in the United States on 16 April 1916. The film was directed by Lois Weber and Phillips Smalley and produced by Universal Film Manufacturing Company/Lois Weber Productions in Universal City, California. In the film, Weber tells a story of an attorney who wants to have children and raise a family, but his wife chooses to abort her pregnancies, fearing that having children will ruin her social activities. In the early 1900s, information about contraception was not freely available or legal to obtain.

Format: Articles

Subject: Publications

Vegas Baby (2016)

In 2016, Runaway Films released the documentary Vegas Baby. The film, directed by Amanda Micheli, follows three women who struggle with infertility problems as they undergo in vitro fertilization, or IVF treatment, to become pregnant. In IVF treatment, a woman’s egg is fertilized by a sperm outside of the woman’s body. Once the sperm fertilizes the egg, a fertility doctor places the fertilized egg back into the woman’s uterus. The three women in the film enter the I Believe contest hosted by the Sher Institute of Reproductive Medicine in Las Vegas, Nevada.

Format: Articles

Subject: Outreach

Ericsson Method of Sperm Separation

In 1973, Ronald Ericsson developed the Ericsson method, which is a technique used to separate human male sperm cells by their genetic material. Ericsson, a physician and reproduction researcher, developed the method while conducting research on sperm isolation in Berlin, Germany, in the early 1970s. He found that the sperm cells that carry male-producing Y chromosomes move through liquid faster than the cells that carry female-producing X chromosomes.

Format: Articles

Subject: Technologies

Camillo Golgi's Black Reaction for Staining Neurons

In 1873 Italy, Camillo Golgi created the black reaction technique, which enabled scientists to stain and view the structure of neurons, the specialized cells that compose the nervous system. During the nineteenth century, scientists were studying cells and proposed cell theory, which describes the basic characteristics of cells as fundamental units of life. However, cell theory struggled to explain neurons as they are specialized cells and more complex in structure than cells of other tissues.

Format: Articles

Subject: Technologies

Park v. Chessin (1977)

The New York Appellate Court ruled on 11 December 1977 in favor of Steven and Hetty Park and against Herbert Chessin for the wrongful life of the Parks' child. In a wrongful life case, a disabled or sometimes deceased child brings suit against a physician for failing to inform its parents of possible genetic defects, thereby causing harm to the child when born. Park v. Chessin was the first case to rule that medical personnel could be legally responsible for wrongful life. Further cases such as the 1979 case Berman v. Allan and the 1982 case Turpin v.

Format: Articles

Subject: Legal, Reproduction

Test-Tube Baby

A test-tube baby is the product of a successful human reproduction that results from methods beyond sexual intercourse between a man and a woman and instead utilizes medical intervention that manipulates both the egg and sperm cells for successful fertilization. The term was originally used to refer to the babies born from the earliest applications of artificial insemination and has now been expanded to refer to children born through the use of in vitro fertilization, the practice of fertilizing an embryo outside of a woman's body.

Format: Articles

Subject: Processes, Ethics, Reproduction

The Case Against Perfection: Ethics in the Age of Genetic Engineering (2007), by Michael J. Sandel

The Case against Perfection: Ethics in the Age of Genetic Engineering, hereafter referred to as The Case against Perfection, written by Michael J. Sandel, builds on a short essay featured in The Atlantic Monthly magazine in 2004. Three years later, Sandel transformed his article into a book, keeping the same title but expanding upon his personal critique of genetic engineering. The purpose of Sandel's book is to articulate the sources of what he considers to be widespread public unease related to genetic engineering that changes the course of natural development.

Format: Articles

Subject: Publications, Ethics

Andrew Zachary Fire (1959- )

Andrew Zachary Fire is a professor at Stanford University and Nobel Laureate. Fire worked at the Carnegie Institution of Washington's Department of Embryology in Baltimore, Maryland, with colleague Craig Mello, where they discovered that RNA molecules could be used to turn off or knock out the expression of genes. Fire and Mello called the process RNA interference (RNAi), and won the Nobel Prize in Physiology or Medicine in 2006 for their discovery.

Format: Articles

Subject: People

Umbilical Cord Blood Stem Cells (UCBSC)

Umbilical cord blood (UCB) stem cells are hematopoietic stem cells (HSC) that are recovered from the blood of the umbilical cord and placenta after birth. Umbilical cord blood is rich in cells that express the CD34 molecule, a surface protein that identifies cells as stem cells. Prior to the discovery of UCB stem cells, it was standard procedure to discard the umbilical cord and placenta; now much effort is devoted to raising public awareness and to encouraging people to store or donate cord blood.

Format: Articles

Subject: Processes, Reproduction

Hysterectomy

A hysterectomy is the surgical removal of a woman's uterus. For many women, a hysterectomy comes as a solution to health problems as diverse as abnormal bleeding to reproductive cancers. First performed in the early 1800s, this procedure has evolved in terms of both technique and popularity. The first successful abdominal hysterectomy was performed by Ellis Burnham in Lowell, Massachusetts, in 1853, although earlier attempts were made in the 1840s.

Format: Articles

Subject: Technologies, Reproduction

Lap-Chee Tsui (1950-)

Lap-Chee Tsui is a geneticist who discovered the cystic fibrosis (CF) gene, and his research team sequenced human chromosome 7. As the location of the cystic fibrosis gene is now known, it is possible for doctors and specialists to identify in human fetuses the mutation that causes the fatal disease. Tsui's research also outlined the mechanisms for the development of cystic fibrosis, which were previously unknown.

Format: Articles

Subject: People, Reproduction

Davis v. Davis [Brief] (1992)

This case was the first of its kind to address questions of personhood in the context of in vitro fertilization of a human embryo. It laid a foundation for future cases to work from: specifically, this case established the importance of prior written agreements for disposition of frozen embryos. This was also the first court decision to borrow the word "pre-embryo" from bioethics to describe the in vitro embryo. This terminology has been copied by many states.

Format: Articles

Subject: Legal, Reproduction

Berman v. Allan (1979)

The Supreme Court of New Jersey decided the case of Berman v. Allan on 26 June 1979, brought by Shirley Berman and Paul Berman and their daughter Sharon Esther Berman against Ronald Allan and Michael Vincent Attardi, Shirley's physicians. The court dismissed the Bermans' claims for what they termed wrongful life of their daughter, but allowed them to claim compensation as a result of what was termed wrongful birth.

Format: Articles

Subject: Legal, Reproduction

Center for Reproductive Health (1986-1995)

The Center for Reproductive Health was a fertility clinic run by a partnership of world-renowned fertility specialists from 1986 to 1995. The Center operated at three clinic locations under affiliation with the University of California Irvine 's Medical Center (UCIMC). The Center's renowned specialists and medical success stories attracted clients worldwide until evidence of highly unethical practices conducted by doctors there resulted in over one hundred lawsuits against the University. At issue was the doctors' misappropriation and unauthorized use of eggs and embryos.

Format: Articles

Subject: Organizations, Reproduction

Alan Mathison Turing (1912-1954)

Alan Mathison Turing was a British mathematician and computer scientist who lived in the early twentieth century. Among important contributions in the field of mathematics, computer science, and philosophy, he developed a mathematical model of morphogenesis. This model describing biological growth became fundamental for research on the process of embryo development.

Format: Articles

Subject: People

Congenital Vertebral Defects

The spinal column is the central structure in the vertebrate body from which stability, movement, and posture all derive. The vertebrae of the spine are organized into four regions (listed in order from cranial to caudal): cervical, thoracic, lumbar, and pelvic. These regions are classified by their differences in curvature. The human spine usually consists of thirty-three vertebrae, seven of which are cervical (C1-C7), twelve are thoracic (T1-T12), five are lumbar (L1-L5), and nine are pelvic (five fused as the sacrum and four fused as the coccyx).

Format: Articles

Subject: Disorders, Reproduction

Abortion

Abortion is the removal of the embryo or fetus from the womb, before birth can occur-either naturally or by induced labor. Prenatal development occurs in three stages: the zygote, or fertilized egg; the embryo, from post-conception to eight weeks; and the fetus, from eight weeks after conception until the baby is born. After abortion, the infant does not and cannot live. Spontaneous abortion is the loss of the infant naturally or accidentally, without the will of the mother. It is more commonly referred to as miscarriage.

Format: Articles

Subject: Processes, Ethics, Reproduction