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Hermaphrodites and the Medical Invention of Sex (1998), by Alice Domurat Dreger

Hermaphrodites and the Medical Invention of Sex, by historian of science Alice Domurat Dreger, was published in 1998 by Harvard University Press. In the book, Dreger describes how many doctors and scientists treated human hermaphrodites from the late nineteenth century to the early twentieth century. She states that during this time period, many physicians and scientists struggled to determine the nature sex, and to support a classification of sex as male or female, many physicians and scientists resorted to viewing a person's gonads for identification of his or her sex.

Format: Articles

Subject: Publications, Theories, Disorders

Free Hospital for Women Scrapbook by Harvard University Library

This scrapbook is part of the Harvard University Library's collection on "Working Women, 1800-1930," which is itself part of the Open Collections Program. The print version is located at the Francis A. Countway Library of Medicine. It contains information about the hospital, including articles from newspapers, magazines, and other publications; photographs of the hospital, employees, and special events; lecture announcements; letters and other forms of correspondence; ration cards; tickets; forms; certificates; posters; programs; and playbills.

Format: Articles

Subject: Organizations, Ethics, Reproduction

Royal College of Obstetricians and Gynaecologists (1929–1970)

Starting in 1929, the Royal College of Obstetricians and Gynaecologists was a professional association of physicians in the UK that aimed to improve the care of women in childbirth through training and education and to establish obstetrics and gynecology as a medical specialty. The Royal College of Obstetricians and Gynaecologists has contributed to women’s reproductive health by fostering research, establishing standards for physicians specializing in obstetrics and gynecology, and influencing legislation.

Format: Articles

Subject: Organizations

Slime mold development video by John Tyler Bonner

This video is composed of a sequence of time lapse films created by John Tyler Bonner in the 1940s to show the life cycle of the cellular slime mold, Dictyostelium discoideum. As only the second person to study slime molds, Bonner frequently encountered audiences who had never heard of, let alone seen, the unusual organism. He therefore decided to create a film to present at seminars in order to introduce his object of study. Bonner created the video for his senior thesis at Harvard University with the help of photographer Frank Smith.

Format: Video

Subject: Organisms

Bernadine Healy (1944–2011)

During the twentieth century in the United States, Bernadine Patricia Healy was a cardiologist who served as the first female director of the National Institutes of Health or NIH and the president of both the American Heart Association and the American Red Cross. Healy conducted research on the different manifestations of heart attacks in women compared to men. At the time, many physicians underdiagnosed and mistreated coronary heart disease in women. Healy's research illustrated how coronary heart disease affected women.

Format: Articles

Subject: People

John Charles Rock (1890-1984)

Born on 24 March 1890 in Marlborough, Massachusetts, to Ann and Frank Rock, John Charles Rock was both a devout Catholic and one of the leading investigators involved in the development of the first oral contraceptive pill. In 1925 he married Anna Thorndike, with whom he later had five children. He spent over thirty years of his career as a clinical professor of obstetrics at Harvard Medical School, and in 1964 the Center for Population Studies of the Harvard School of Public Health established the John Rock Professorship.

Format: Articles

Subject: People, Reproduction

Minnie Joycelyn Elders (1933–)

Minnie Joycelyn Elders, known as Joycelyn Elders, is a pediatrician and professor at the University of Arkansas for Medical Sciences in Little Rock, Arkansas. In 1953, Elders began to work with the US Army, where she trained as a physical therapist, being the only African American woman in her training class. Elders eventually became a medical doctor in 1956, specializing in pediatric endocrinology. In 1993, then US President Bill Clinton appointed Elders as the Surgeon General for the United States Public Health Service Commissioned Corps, which she served as until 1994.

Format: Articles

Subject: People

David Hunter Hubel (1926–2013)

David Hunter Hubel studied the development of the visual system and how the brain processes visual information in the US during the twentieth century. He performed multiple experiments with kittens in which he sewed kitten’s eyes shut for varying periods of time and monitored their vision after reopening them. Hubel, along with colleague Torsten Wiesel, received the 1981 Nobel Prize in Physiology or Medicine for that research.

Format: Articles

Subject: People

Norbert Freinkel (1926–1989)

During the twentieth century, Norbert Freinkel studied hormones and diabetes in the US. Freinkel conducted many experiments that enabled him to determine the factors that influence hormones of the thyroid gland to bind to proteins and to determine the effects that those thyroid hormones have on surrounding tissues. Furthermore, Freinkel researched gestational diabetes, which is diabetes that occurs for the first time during a women’s pregnancy. That type of diabetes is caused by a change in the way a woman’s body responds to insulin, a hormone made in the body.

Format: Articles

Subject: People

Stephen Jay Gould (1941-2002)

Stephen Jay Gould studied snail fossils and worked at Harvard University in Cambridge, Massachusetts during the latter half of the twentieth century. He contributed to philosophical, historical, and scientific ideas in paleontology, evolutionary theory, and developmental biology. Gould, with Niles Eldredge, proposed the theory of punctuated equilibrium, a view of evolution by which species undergo long periods of stasis followed by rapid changes over relatively short periods instead of continually accumulating slow changes over millions of years.

Format: Articles

Subject: People

Amenorrhea as a Menstrual Disorder

Amenorrhea is considered a type of abnormal menstrual bleeding characterized by the unexpected absence of menstrual bleeding, lasting three months or longer. Menstrual bleeding typically happens approximately once a month when blood and endometrial tissue, or tissue lining the inside of the uterus, sheds from the uterus through the vagina. Menstruation is expected to stop with pregnancy, breastfeeding, and menopause, or the natural cessation of the menstrual cycle at an older age.

Format: Articles

Subject: Disorders, Reproduction

"The Contagiousness of Puerperal Fever” (1843), by Oliver Wendell Holmes

In 1843, physician Oliver Wendell Holmes wrote and published The Contagiousness of Puerperal Fever, an essay about puerperal fever, a disease that occurs mainly as a result of bacterial infection in the uterine tract of women after giving birth or undergoing an abortion. In the essay, Holmes argues that puerperal fever is spread through birth attendants like physicians and midwives who make contact with the disease and carry it from patient to patient. The article was published in The New England Quarterly Journal of Medicine and Surgery in 1843.

Format: Articles

Subject: Publications

“The Emergence of Developmental Psychopathology” (1984), by Dante Cicchetti

In 1984, Dante Cicchetti published “The Emergence of Developmental Psychopathology,” an article in which he argued that the previously amorphous study of developmental psychopathology was emerging as a unified discipline. According to Cicchetti, developmental psychopathology describes an interdisciplinary field that studies abnormalities in psychological function that can arise during human development.

Format: Articles

Subject: Publications

George Linius Streeter (1873-1948)

George Linius Streeter was born on 12 January 1873 in Johnstown, New York, to Hannah Green Anthony and George Austin Streeter. He completed his undergraduate studies at Union College in 1895 and received his MD degree from the College of Physicians and Surgeons of Columbia University in 1899. At Columbia, Professor George S. Huntington sparked Streeter's interest in anatomy, and Streeter also interned at Roosevelt Hospital in New York City. He then went on to Albany to teach anatomy at the Albany Medical College and to work with neurologist Henry Hun.

Format: Articles

Subject: People

George McDonald Church (1954- )

George McDonald Church studied DNA from living and from extinct species in the US during the twentieth and twenty-first centuries. Church helped to develop and refine techniques with which to describe the complete sequence of all the DNA nucleotides in an organism's genome, techniques such as multiplex sequencing, polony sequencing, and nanopore sequencing. Church also contributed to the Human Genome Project, and in 2005 he helped start a company, the Personal Genome Project. Church proposed to use DNA from extinct species to clone and breed new organisms from those species.

Format: Articles

Subject: People, Technologies

Kurt Benirschke (1924-)

Kurt Benirschke studied cells, placentas, and endangered species in Germany and the US during the twentieth century. Benirschke was professor at the University of California in San Diego, California, and a director of the research department at the San Diego Zoo in San Diego, California. He also helped form the research department of the San Diego Zoo and its sister organization, the Center for Reproduction of Endangered Species.

Format: Articles

Subject: People

Gavin Rylands de Beer (1899-1972)

Gavin de Beer was an English zoologist known for his contributions to evolution and embryology, in particular for showing the inadequacy of the germ layer theory as it was then proposed. He was born in London, England, on 1 November 1899, but was raised for his first thirteen years in France where his father worked for a telegraph company. He entered Magdalen College, Oxford, in 1917 but his studies were soon interrupted by World War I. After serving in the military, he returned to Oxford where he studied under Edwin Goodrich.

Format: Articles

Subject: People

William Stewart Halsted (1852-1922)

William Stewart Halsted was a surgeon at Johns Hopkins Hospital in Baltimore, Maryland, during the late 1800s and early 1900s. In 1894 Halsted described his procedure for treating breast cancer by removing the breast tissue, chest muscles, and lymph nodes in the armpit, a procedure he named radical mastectomy, and that became the standard of care for treating breast cancer until 1970.

Format: Articles

Subject: People

"The Development of the Turtle Carapace" (1989), by Ann Campbell Burke

Ann Campbell Burke examines the development and evolution of vertebrates, in particular, turtles. Her Harvard University experiments, described in Development of the Turtle Carapace: Implications for the Evolution of a Novel Bauplan, were published in 1989. Burke used molecular techniques to investigate the developmental mechanisms responsible for the formation of the turtle shell.

Format: Articles

Subject: Experiments, Publications

Matthew Howard Kaufman (1942–2013)

Matthew Kaufman was a professor of anatomy at the University of Edinburgh, in Edinburgh, UK, who specialized in mouse anatomy, development, and embryology during the late twentieth century. According to the The Herald, he was the first, alongside his colleague Martin Evans, to isolate and culture embryonic stem cells. Researchers initially called those cells Evans-Kaufman cells. In 1992, Kaufman published The Atlas of Mouse Development, a book that included photographs of mice development and mice organs over time.

Format: Articles

Subject: People

Rosalind Elsie Franklin (1920-1958)

Rosalind Elsie Franklin worked with X-ray crystallography at King's College London, UK, and she helped determine the helical structure of DNA in the early 1950s. Franklin's research helped establish molecular genetics, a field that investigates how heredity works on the molecular level. The discovery of the structure of DNA also made future research possible into the molecular basis of embryonic development, genetic disorders, and gene manipulation.

Format: Articles

Subject: People

Zhang Lizhu (1921- )

Zhang Lizhu is a Chinese gynecologist and researcher. For most of her career, she worked in the Peking Medical College Third Hospital, renamed in 2000, Peking University Third Hospital. There, she led a team of researchers and physicians in the study of human in vitro fertilization (IVF) and embryo transfer (ET) technology. Zhang and her colleagues contributed to the birth of the first test-tube baby in Mainland China in 1988.

Format: Articles

Subject: People, Reproduction

Studies in Spermatogenesis (1905), by Nettie Maria Stevens

Studies in Spermatogenesis is a two volume book written by Nettie Maria Stevens, and published by the Carnegie Institution of Washington in 1905 and 1906. In the books Stevens explains the research she conducted on chromosomal sex determination in the sperm and egg cells of insect species while at Bryn Mawr College, near Philadelphia, Pennsylvania. Studies in Spermatogenesis described early examples of chromosomal XY sex-determination.

Format: Articles

Subject: Publications

James Young Simpson (1811–1870)

James Young Simpson was one of the first obstetricians to administer anesthesia during childbirth in nineteenth century Scotland. Before his work in the 1800s, physicians had few ways to reduce the pain of childbirth. Simpson experimented with the use of ether and chloroform, both gaseous chemicals, to temporarily relieve pain. He found that those chemicals both successfully inhibited the pain women felt during childbirth and pain during other surgeries. Patients under the influence of chloroform fell asleep and were unaware of the intense pain of childbirth.

Format: Articles

Subject: People

Light Therapy for Neonatal Jaundice

Light therapy, also called phototherapy, exposes infants with jaundice, a yellowing of the skin and eyes, to artificial or natural light to break down the buildup of bilirubin pigment in the blood. Bilirubin is an orange to red pigment produced when red blood cells break down, which causes infants to turn into a yellowish color. Small amounts of bilirubin in the blood are normal, but when there is an accumulation of excess bilirubin pigment, the body deposits the excess bilirubin in the layer of fat beneath the skin.

Format: Articles

Subject: Technologies

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