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Displaying 76 - 100 of 356 items.

Julia Bell (1879-1979)

Julia Bell worked in twentieth-century Britain, discovered Fragile X Syndrome, and helped find heritable elements of other developmental and genetic disorders. Bell also wrote much of the five volume Treasury of Human Inheritance, a collection about genetics and genetic disorders. Bell researched until late in life, authoring an original research article on the effects of the rubella virus of fetal development (Congenital Rubella Syndrome) at the age of 80.

Format: Articles

Subject: People

Thesis: Dismantling Legal Constraints to Contraception in the 1900s

In the late nineteenth century, the Comstock Act of 1873 made the distribution of contraception illegal and classified contraception as an obscenity. Reflecting the predominant attitude towards contraception at the time, the Comstock Act was the first federal anti-obscenity law that targeted contraception. However, social acceptance of birth control changed at the turn of the twentieth century. In this thesis, I analyzed legislation, advocates, and literature pertinent to that social change to report on the events leading up to the decriminalization of contraception.

Format: Essays and Theses

Subject: People, Legal, Reproduction

Thesis: Reproduction in Science Fiction

Science fiction works can reflect the relationship between science and society by telling stories that are set in the future of ethical implications or social consequences of scientific advancements. This thesis investigates how the concept of reproduction is depicted in popular science fiction works.

Format: Essays and Theses

Subject: Publications, Reproduction

William Keith Brooks (1848-1908)

Biologist William Keith Brooks studied embryological development in invertebrates and used his results as evidence for theories of evolution and ancestral heredity. He founded a marine biological laboratory where his and others' embryological studies took place. Later in life, Brooks became head of the Biology Department at Johns Hopkins University where he helped shape the minds of leading embryologists.

Format: Articles

Subject: People

Virginia Apgar (1909-1974)

Virginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women’s pain during childbirth, in the US in the mid-twentieth century. In 1953, Apgar created a scoring system using five easily assessable measurements, including heart rate and breathing rate, to evaluate whether or not infants would benefit from medical attention immediately after birth. Apgar’s system showed that infants who were previously set aside as too sick to survive, despite low Apgar scores, could recover with immediate medical attention.

Format: Articles

Subject: People, Reproduction

George Frederic Still (1868–1941)

George Frederic Still studied pediatrics and childhood conditions in England during the early twentieth century. In Still’s time, pediatrics, or the branch of medicine that focuses on treating and caring for children, remained largely unexplored according to biographer Joseph deBettencourt. Still helped advance pediatrics as a field by classifying and writing about diseases and conditions that arose in children. In 1897, he discovered a unique type of arthritis in children, now referred to as Still’s disease.

Format: Articles

Subject: People

James Marion Sims (1813-1883)

James Marion Sims developed a surgical cure for ruptures of the wall separating the bladder from the vagina during labor, ruptures called vesico-vaginal fistulas, and he developed techniques and tools used to improve reproductive examinations and health care for women in the US during the nineteenth century. Sims's lateral examination position allowed doctors to better see the vaginal cavity, and his speculum, a spoon-like object used for increased view into the vagina, helped to make gynecological examinations more thorough.

Format: Articles

Subject: People, Reproduction

Francis Harry Compton Crick (1916-2004)

Francis Harry Compton Crick, who co-discovered the structure of deoxyribonucleic acid (DNA) in 1953 in Cambridge, England, also developed The Central Dogma of Molecular Biology, and further clarified the relationship between nucleotides and protein synthesis. Crick received the Nobel Prize in Physiology or Medicine that he shared with James Watson and Maurice Wilkins in 1962 for their discovery of the molecular structure of DNA.

Format: Articles

Subject: People

Robert William Briggs (1911-1983)

Robert William Briggs was a prolific developmental biologist. However, he is most identified with the first successful cloning of a frog by nuclear transplantation. His later studies focused on the problem of how genes influence development.

Format: Articles

Subject: People

Muriel Wheldale Onslow (1880-1932)

Muriel Wheldale Onslow studied flowers in England with genetic and biochemical techniques in the early twentieth century. Working with geneticist William Bateson, Onslow used Mendelian principles and biochemical analysis together to understand the inheritance of flower colors at the beginning of the twentieth century. Onslow's study of snapdragons, or Antirrhinum majus, resulted in her description of epistasis, a phenomenon in which the phenotypic effect of one gene is influenced by one or more other genes. She discovered several biochemicals related to color formation.

Format: Articles

Subject: People

William Harvey (1578-1657)

Renowned physician and scientist William Harvey is best known for his accurate description of how blood circulates through the body. While his published work on the circulation of blood is considered the most important of his academic life, Harvey also made significant contributions to embryology with the publication of his book Exercitationes de Generatione Animalium in 1651. In this book he established several theories that would set the stage for modern embryology and addressed many embryological issues including conception, embryogenesis, and spontaneous generation.

Format: Articles

Subject: People

Arthur William Galston (1920–2008)

Arthur W. Galston studied plant hormones in the United States during the late-twentieth century. His dissertation on the flowering process of soybean plants led others to develop Agent Orange, the most widely employed herbicide during the Vietnam War, used to defoliate forests and eliminate enemy cover and food sources. Galston protested the spraying of those defoliants in Vietnam, as they could be harmful to humans, animals, and the environment.

Format: Articles

Subject: People

Joseph Needham (1900-1995)

Joseph Needham was an embryologist and biochemist who is most noted in science for his studies on induction in developing embryos. Needham worked with Conrad Hal Waddington to attempt to identify the compound responsible for the organizer's activity. Although he was not successful in discovering the chemical, he and Waddington learned much about the organizer. Needham was a meticulous writer, writing reviews and books about contemporary research.

Format: Articles

Subject: People

Anne Laura Dorinthea McLaren (1927-2007)

Anne Laura Dorinthea McLaren was a developmental biologist known for her work with embryology in the twentieth century. McLaren was the first researcher to grow mouse embryos outside of the womb. She experimented by culturing mouse eggs and successfully developing them into embryos, leading to advancements with in vitro fertilization.

Format: Articles

Subject: People

William Bateson (1861-1926)

At the turn of the twentieth century, William Bateson studied organismal variation and heredity of traits within the framework of evolutionary theory in England. Bateson applied Gregor Mendel's work to Charles Darwin's theory of evolution and coined the term genetics for a new biological discipline. By studying variation and advocating Mendelian genetics, Bateson furthered the field of genetics, encouraged the use of experimental methodology to study heredity, and contributed to later theories of genetic inheritance.

Format: Articles

Subject: People

Jeffrey Keenan (1961- )

Jeffrey Keenan is the Director of the Southeastern Center for Fertility and Reproductive Medicine and the main developer behind the National Embryo Donation Center (NEDC) in Knoxville, Tennessee. This non-profit organization focuses on embryo donation and embryo adoption.

Format: Articles

Subject: People, Reproduction

Conrad Hal Waddington (1905-1975)

Conrad Hal Waddington was an embryologist and theoretical biologist. His early experimental work investigated aspects of embryonic induction and the properties of the organizer first identified by Hans Spemann and Hilde Mangold, while his later studies focused on genetic assimilation. Waddington is probably best known for developing the concept of the epigenetic landscape, and he also held significant interest in many different areas ranging from the visual arts and poetry to philosophy.

Format: Articles

Subject: People

Nicole Marthe Le Douarin (1930- )

Nicole Marthe Le Douarin was one of the first progressive female pioneers of developmental and embryological research. Some of her most notable and ground-breaking work involves grafting quail and chicken embryos together in order to study the developmental fate of each contributing embryo. Le Douarin was born in Brittany, France, on 20 August 1930. As an only child she was inspired by her mother, a school teacher at the time, to develop a passion for learning.

Format: Articles

Subject: People

Clifford Grobstein (1916-1998)

Clifford Grobstein was a traditional, influential, and highly innovative biologist of the mid-twentieth century, gifted with many character facets and pragmatic talents. His early adulthood passion of linking classical embryology with developmental anatomy and medicine was joined by his later pursuit of combining research ethics and science education with public policy.

Format: Articles

Subject: People

Sir D'Arcy Wentworth Thompson (1860-1948)

Known by many for his wide-reaching interests and keen thinking, D'Arcy Wentworth Thompson was one of Britain's leading scientific academics in the first few decades of the twentieth century. A prodigious author, Thompson published some 300 papers, books, and articles in the biological sciences, classics, oceanography, and mathematics. He was a famous lecturer and conversationalist-a true "scholar-naturalist," as his daughter wrote in her biography of her father.

Format: Articles

Subject: People

Leon Richard Kass (1939- )

A PhD and medical doctor turned ethicist, Leon Kass calls himself an unlicensed humanist. Throughout his unique career he has sought to impact others and engage important cultural issues. This he has accomplished over the course of many years by studying biochemistry, teaching humanities, writing articles and books on ethics, and serving as chair of the President's Council on Bioethics.

Format: Articles

Subject: People, Ethics, Reproduction

Thesis: The Hwang Woo-Suk Scandal and the Development of Bioethics in South Korea

In 2004, the South Korean geneticist Woo-Suk Hwang published what was widely regarded as the most important research finding in biotechnology that year. In the prestigious American journal Science, he claimed that he had succeeded in cloning a human blastocyst, which is an embryo in its early developmental stages (Hwang et al. 2004). A year later, in a second Science article, he made the earth-shattering announcement that he had derived eleven embryonic stem cell lines using his cloning technique (Hwang et al. 2005). The international scientific community was stunned.

Format: Essays and Theses

Subject: Ethics, People

Thesis: Visualizing the Embryo: Establishing Procedures for Digital Image Production with the Embryo Project

Until 2013, the Embryo Project Encyclopedia had not presented images in articles due to the fact that there was no formal protocol for developing images at that time. I have created an image style guide that outlines the basic steps of creating and submitting an image that can complement an Embryo Project article and can enhance a reader’s understanding of the discussed concept. In creating this style guide, I investigate similar protocols used by other scientific journals and medical professionals.

Format: Essays and Theses

Subject: Outreach

Thesis: Surprising Religious and Republican Roots to Planned Parenthood: An Arizona Case Study

The social and political history surrounding Planned Parenthood Arizona illustrates the interplay between politics and the reproductive rights movement throughout the twentieth century. The contextualization of major historical events during the development of Planned Parenthood Arizona gives insight into the current political and religious beliefs regarding the reproductive rights movement.

Format: Essays and Theses

Subject: Organizations, Places, Religion

Thesis: From Monsters to Medicine: A Historical Analysis of Changes in the Field of Teratology Over the Twentieth Century

This project focuses on the history of how teratogens, or agents which have the potential to cause birth defects, have been understood and tested for teratogenic potential in the US over the twentieth century. Prior to this time, teratogen studies were primarily concerned with cataloguing defects rather than exploring possible causes. At the turn of the twentieth century, experimental teratogen studies with the aim of elucidating mechanisms commenced.

Format: Essays and Theses

Subject: Disorders