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Displaying 826 - 850 of 1047 items.

"Experiments in Plant Hybridization" (1866), by Johann Gregor Mendel

During the mid-nineteenth century, Johann Gregor Mendel experimented with pea plants to develop a theory of inheritance. In 1843, while a monk in the Augustian St Thomas's Abbey in Brünn, Austria, now Brno, Czech Repubic, Mendel examined the physical appearance of the abbey's pea plants (Pisum sativum) and noted inconsistencies between what he saw and what the blending theory of inheritance, a primary model of inheritance at the time, predicted.

Format: Articles

Subject: Experiments

In the Matter of the Marriage of Dahl and Angle (2008)

In the 2008 court case In the Matter of the Marriage of Dahl and Angle, the Court of Appeals of Oregon upheld a written in vitro fertilization (IVF) consent form signed by Laura and Darrell Angle, who had each contributed their genetic material to the creation of several preembryos during their marriage. Its decision followed the general framework for resolving such disputes provided by the Supreme Court of Tennessee in Davis v. Davis in 1992, which was subsequently followed by many courts across the US.

Format: Articles

Subject: Legal

"Cellular death in morphogenesis of the avian wing" (1962), by John W. Saunders Jr., et al.

In the early 1960s, John W. Saunders Jr., Mary T. Gasseling, and Lilyan C. Saunders in the US investigated how cells die in the developing limbs of chick embryos. They studied when and where in developing limbs many cells die, and they studied the functions of cell death in wing development. At a time when only a few developmental biologists studied cell death, or apoptosis, Saunders and his colleagues showed that researchers could use embryological experiments to uncover the causal mechanisms of apotosis.

Format: Articles

Subject: Experiments

Paul Kammerer's Experiments on the Midwife Toad (1905-1910)

In the first decade of the twentieth century, Paul Kammerer, a zoologist working at the Vivarium in Vienna, Austria, conducted research on developmental mechanisms, including a series of breeding experiments on toads (Alytes obstetricans). Kammerer claimed that his results demonstrated that organisms could transmit acquired characteristics to their offspring.

Format: Articles

Subject: Experiments

Stanley Alan Plotkin's Development of a Rubella Vaccine (1969)

In the US during the late 1960s, Stanley Alan Plotkin, John D. Farquhar, Michael Katz, and Fritz Buser isolated a strain of the infectious disease rubella and developed a rubella vaccine with a weakened, or attenuated, version of the virus strain. Rubella, also called German measles, is a highly contagious disease caused by the rubella virus that generally causes mild rashes and fever. However, in pregnant women, rubella infections can lead to developmental defects in their fetuses.

Format: Articles

Subject: Experiments

Texas Medical Providers Performing Abortion Services v. Lakey (2012)

In the 2012 case Texas Medical Providers Performing Abortion Services v. David Lakey, a US appeals court ruled as constitutional a Texas law that required abortion providers in the state to show women receiving abortions the ultrasound images of their fetuses. The law also required providers to describe the sounds of the fetuses' nascent hearts. In doing so, the court set precedent that ultrasound readings are necessary medical information for pregnant women seeking abortions, increasing the wait-period for women seeking abortions.

Format: Articles

Subject: Legal

Transposition of the Great Arteries (TGA)

Transposition of the great arteries or TGA is a potentially fatal congenital heart malformation where the pulmonary artery and the aorta are switched. The switch means that the aorta, which normally carries oxygenated blood, carries deoxygenated blood. There are two types of the malformation, d-TGA where no oxygen reaches the body and l-TGA where some oxygenated blood circulates. In the US, the Centers for Disease Control estimate that about 1,901 infants are born each year with TGA, or about one for every 2,000 births.

Format: Articles

Subject: Disorders

Anthony Comstock (1844–1915)

Anthony Comstock was a US postal inspector and politician who advocated for the suppression of obscenity and vice throughout the late nineteenth century and early twentieth century. Comstock considered any sexually explicit material like pornography and literature related to birth control and abortion as obscene. In 1873, Comstock lobbied US Congress to pass an anti-obscenity law titled An Act for the Suppression of Trade in, and Circulation of, Obscene Literature and Articles of Immoral Use, also called the Comstock Act.

Format: Articles

Subject: People

Amphioxus, and the Mosaic Theory of Development (1893), by Edmund Beecher Wilson

Edmund Beecher Wilson experimented with Amphioxus (Branchiostoma) embryos in 1892 to identify what caused their cells to differentiate into new types of cells during the process of development. Wilson shook apart the cells at early stages of embryonic development, and he observed the development of the isolated cells. He observed that in the normal development of Amphioxus, all three main types of symmetry, or cleavage patterns observed in embryos, could be found. Wilson proposed a hypothesis that reformed the Mosaic Theory associated with Wilhelm Roux in Germany.

Format: Articles

Subject: Experiments

“Family Limitations” (1914), by Margaret Higgins Sanger

In 1914, Margaret Sanger published “Family Limitations,” a pamphlet describing six different types of contraceptive methods. At the time Sanger published the pamphlet, the federal Comstock Act of 1873 had made distributing contraceptive and abortion information through the US postal service illegal. The Comstock Act classified contraceptive information as obscene and limited the amount of information available to individuals about preventing pregnancies.

Format: Articles

Subject: Publications

The Development of Mifepristone for Use in Medication Abortions

In the 1980s, researchers at the pharmaceutical company Roussel-Uclaf in Paris, France, helped develop a biological compound called mifepristone. When a woman takes it, mifepristone interferes with the function of hormones involved in pregnancy and it can therefore be used to terminate pregnancies. In 2000, the US Food and Drug Administration approved mifepristone, also called RU 486, as part of a treatment to induce abortions using drugs instead of surgery, a method called medication abortion.

Format: Articles

Subject: Reproduction

"Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women" (1971), by Arthur L. Herbst, et al.

Published in 1971, Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, by Arthurs L. Herbst and colleagues, was the first piece of literature connecting maternal use of the drug diethylstilbestrol (DES), also called stilbestrol, with the development of a rare and severe form of vaginal cancer in young women. Diethylstilbestrol was later classified as an endocrine disruptor, a substance that disrupts the hormonal function of the body in those exposed to it during development or later in life.

Format: Articles

Subject: Publications

Etienne Stephane Tarnier (1828–1897)

Etienne Stephane Tarnier was a physician who worked with premature infants in France during the nineteenth century. He worked at the Maternité Port-Royal in
Paris, France, a hospital for poor pregnant women. Tarnier developed and introduced prototypes of
infant incubators to the Maternité in 1881. Tarnier's incubators became standard in neonatal care,
especially for premature infants, enabling doctors to save many such infants that previously would
have died.

Format: Articles

Subject: People

Freedom of Access to Clinic Entrances Act (1994)

On 26 May 1994, US President Bill Clinton signed the Freedom of Access to Clinic Entrances Act in to law, which federally criminalized acts of obstruction and violence towards reproductive health clinics. The law was a reaction to the increasing violence toward abortion clinics, providers, and patients during the 1990s. That violence included clinic blockades and protests, assaults on physicians and patients, and murders. The Freedom of Access to Clinic Entrances Act established

Format: Articles

Subject: Legal

What Every Mother Should Know (1914), by Margaret Sanger

What Every Mother Should Know was published in 1914 in New York City, New York, as a compilation of newspaper articles written by Margaret Sanger in 1911. The series of articles informed parents about how to teach their children about reproduction and it appeared in the newspaper New York Call. In 1911, the newspaper series was published as a book, with several subsequent editions appearing later. In What Every Mother Should Know, Sanger emphasizes starting education on reproduction early and honestly answering children’s questions.

Format: Articles

Subject: Publications

Chang and Eng Bunker (1811–1874)

Chāng (Chang) and Ēn (Eng) Bunker were conjoined twins in the nineteenth century in the United States, the first pair of conjoined twins whose condition was well documented in medical records. A conjoined twins is a rare condition in which two infants are born physically connected to each other. In their youth, the brothers earned money by putting themselves on display as curiosities and giving lectures and demonstrations about their condition. The Bunker brothers toured around the world, including the United States, Europe, Canada, and France, and allowed physicians to examine them.

Format: Articles

Subject: People

Litowitz v. Litowitz (2002)

In a dispute over the allocation of cryopreserved preembryos, the Supreme Court of Washington resolved the case of David J. Litowitz v. Becky M. Litowitz (2002) by reaching a decision that neither party wanted. David Litowitz sought to find adoptive parents for two cryopreserved preembryos created during his marriage to Becky Litowitz when the couple was attempting to have children using in vitro fertilization (IVF). Becky sought to implant the preembryos in a surrogate in an effort to parent a child.

Format: Articles

Subject: Legal

Wilhelm Johannsen's Genotype-Phenotype Distinction

Wilhelm Johannsen in Denmark first proposed the distinction between genotype and phenotype in the study of heredity in 1909. This distinction is between the hereditary dispositions of organisms (their genotypes) and the ways in which those dispositions manifest themselves in the physical characteristics of those organisms (their phenotypes). This distinction was an outgrowth of Johannsen's experiments concerning heritable variation in plants, and it influenced his pure line theory of heredity.

Format: Articles

Subject: Theories

"Screening for Congenital Hypothyroidism" (1991), by Delbert A. Fisher

In his 1991 article Screening for Congenital Hypothyroidism, Delbert A. Fisher in the US reported on the implementation and impact of mass neonatal screening programs for congenital hypothyroidism (CH) from the early 1970s through 1991. CH is a condition that causes stunted mental and physical development in newborns unless treatment begins within the first three months of the newborn's life. In the early 1970s, regions in Canada and the US had implemented screening programs to diagnose and treat CH as quickly as possible after the infant's birth.

Format: Articles

Subject: Publications, Technologies

Eugenical Sterilization in the United States (1922), by Harry H. Laughlin

Eugenical Sterilization in the United States is a 1922 book in which author Harry H. Laughlin argues for the necessity of compulsory sterilization in the United States based on the principles of eugenics. The eugenics movement of the early twentieth century in the US focused on altering the genetic makeup of the US population by regulating immigration and sterilization, and by discouraging interracial procreation, then called miscegenation.

Format: Articles

Subject: Outreach, Legal, Ethics, Publications

The Genetic Control and Cytoplasmic Expression of 'Inducibility' in the synthesis of B-galactosidase" (1959), by Arthur B. Pardee, Francois Jacob, and Jacques Monod

Between 1957 and 1959, Arthur Pardee, Francois Jacob, and Jacques Monod conducted a set of experiments at the Pasteur Institute in Paris, France, that was later called the PaJaMa Experiments, a moniker derived from the researchers' last names. In these experiments, they described how genes of a species of single-celled bacteria, called Escherichia coli (E. coli), controlled the processes by which enzymes were produced in those bacteria.

Format: Articles

Subject: Experiments

David Reimer and John Money Gender Reassignment Controversy: The John/Joan Case

In the mid-1960s, psychologist John Money encouraged the gender reassignment of David Reimer, who was born a biological male but suffered irreparable damage to his penis as an infant. Born in 1965 as Bruce Reimer, his penis was irreparably damaged during infancy due to a failed circumcision. After encouragement from Money, Reimer’s parents decided to raise Reimer as a girl. Reimer underwent surgery as an infant to construct rudimentary female genitals, and was given female hormones during puberty.

Format: Articles

Subject: Theories

Planned Parenthood Committee of Phoenix v. Maricopa County (1962)

In the 1962 case Planned Parenthood Committee of Phoenix v. Maricopa County, the Arizona Supreme Court ruled that Arizona Revised Statute 13-213, which banned the public advertising of contraceptive or abortion medication or services, was constitutional. However, the court also ruled that that Arizona Revised Statute 13-213 did not apply to Planned Parenthood's distribution of contraceptive information, allowing Planned Parenthood to continue distributing the information.

Format: Articles

Subject: Legal, Organizations

Ann Trow (Madame Restell) (1812–1878)

Self-proclaimed female physician Ann Trow was a women’s reproductive health specialist as well as an abortion provider in New York City, New York during the mid 1800s. Though she had no formal medical training or background, Trow provided women with healthcare and abortions under the alias Madame Restell. Restell gained attention across the United States for her career as a professional abortionist during a time when abortions were highly regulated and punishable with imprisonment. Restell was tried numerous times for carrying out abortions.

Format: Articles

Subject: People