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"Ethical Issues in Human Stem Cell Research: Executive Summary" (1999), by the US National Bioethics Advisory Commission

Ethical Issues in Human Stem Cell Research: Executive Summary was published in September 1999 by The US National Bioethics Advisory Commission in response to a national debate about whether or not the US federal government should fund embryonic stem cell research. Ethical Issues in Human Stem Cell Research recommended policy to US President William Clinton's administration, which advocated for federal spending on the use of stem research on stem cells that came from embryos left over from in vitro fertilization (IVF) fertility treatments.

Format: Articles

Subject: Legal, Ethics

The Excommunication of Margaret McBride (2009–2010)

In 2010, the Catholic Church excommunicated Margaret McBride, a nun and ethics board member at St. Joseph’s Hospital and Medical Center in Phoenix, Arizona. McBride was excommunicated latae sententiae, or automatically, for approving a therapeutic abortion, which is an abortion that is required to save a pregnant woman’s life. McBride approved an abortion for a woman who was twenty-seven years old, eleven weeks pregnant with her fifth child, and suffered from pulmonary hypertension, a life-threatening condition during pregnancy. Following McBride’s decision, St.

Format: Articles

Subject: Ethics

HeLa Cell Line

The HeLa cell line was the first immortal human cell line that George Otto Gey, Margaret Gey, and Mary Kucibek first isolated from Henrietta Lacks and developed at The Johns Hopkins Hospital in Baltimore, Maryland, in 1951. An immortal human cell line is a cluster of cells that continuously multiply on their own outside of the human from which they originated. Scientists use immortal human cell lines in their research to investigate how cells function in humans.

Format: Articles

Subject: Technologies, Experiments, People, Ethics

Leon Richard Kass (1939- )

A PhD and medical doctor turned ethicist, Leon Kass calls himself an unlicensed humanist. Throughout his unique career he has sought to impact others and engage important cultural issues. This he has accomplished over the course of many years by studying biochemistry, teaching humanities, writing articles and books on ethics, and serving as chair of the President's Council on Bioethics.

Format: Articles

Subject: People, Ethics, Reproduction

The US President's Council on Bioethics (2001-2009)

The US President's Council on Bioethics was an organization headquartered in Washington D.C. that was chartered to advise then US President George W. Bush on ethical issues related to biomedical science and technology. In November 2001, US President George W. Bush created the President's Council on Bioethics (PCB). Convened during a nationwide cloning and embryonic stem cell research debate, the Council stated that it worked to address arguments about ethics from many different perspectives.

Format: Articles

Subject: Organizations, Legal, Ethics

Mills v. Board of Education of District of Columbia (1972)

In Mills v. Board of Education of District of Columbia (1972), the United States District Court for the District of Columbia held that students with disabilities are entitled to an education, and that education cannot be denied based on the accommodations’ additional cost to the school. Mills was a class action lawsuit brought to the court on behalf of seven children denied public education by the District of Columbia School District because of their disabilities and the cost of accommodations the school would incur to educate them.

Format: Articles

Subject: Legal, Ethics, Disorders

Free Hospital for Women Scrapbook by Harvard University Library

This scrapbook is part of the Harvard University Library's collection on "Working Women, 1800-1930," which is itself part of the Open Collections Program. The print version is located at the Francis A. Countway Library of Medicine. It contains information about the hospital, including articles from newspapers, magazines, and other publications; photographs of the hospital, employees, and special events; lecture announcements; letters and other forms of correspondence; ration cards; tickets; forms; certificates; posters; programs; and playbills.

Format: Articles

Subject: Organizations, Ethics, Reproduction

In re Agent Orange Product Liability Litigation (1979-1984)

In the legal case In re Agent Orange Product Liability Litigation of the early 1980s, US military veterans of the Vietnam War sued the US chemical companies that had produced the herbicide Agent Orange, and those companies settled with US veterans out of court. Agent Orange contains dioxin, a chemical later shown to disrupt the hormone system of the body and to cause cancer. As veterans returned to the US from Vietnam, scientists further confirmed that exposure to Agent Orange caused a variety of cancers in veterans and developmental problems in the veterans' children.

Format: Articles

Subject: Legal, Ethics

Quickening

Quickening, the point at which a pregnant woman can first feel the movements of the growing embryo or fetus, has long been considered a pivotal moment in pregnancy. Over time, this experience has been used in a variety of contexts, ranging from representing the point of ensoulment to determining whether an abortion was legal to indicating the gender of the unborn baby; philosophy, theology, and law all address the idea of quickening in detail. Beginning with Aristotle, quickening divided the developmental stages of embryo and fetus.

Format: Articles

Subject: Processes, Ethics, Reproduction

Henrietta Lacks (1920–1951)

Henrietta Lacks, born Loretta Pleasant, had terminal cervical cancer in 1951, and was diagnosed at The Johns Hopkins University in Baltimore, Maryland, where researchers collected and stored her cancer cells. Those cells went on to become the first immortal human cell line, which the researchers named HeLa. An immortal cell line is an atypical cluster of cells that continuously multiply on their own outside of the organism from which they came, often due to a mutation.

Format: Articles

Subject: People, Ethics

Stump v. Sparkman (1978)

On March 28, 1978, in Stump v. Sparkman, hereafter Stump, the United States Supreme Court held, in a five-to-three decision, that judges have absolute immunity from lawsuits involving any harm their judicial decisions cause. Linda Sparkman, who was unknowingly sterilized when she was fifteen years old in 1971, sued Harold Stump, the county circuit court judge who signed the petition to allow Sparkman’s mother to have her sterilized. Sparkman’s mother stated to Stump that she wanted her daughter sterilized because of Sparkman’s alleged mental deficiencies and sexual promiscuity.

Format: Articles

Subject: Legal, Ethics, Reproduction

Revive & Restore’s Woolly Mammoth Revival Project

In 2015, Revive & Restore launched the Woolly Mammoth Revival Project with a goal of engineering a creature with genes from the woolly mammoth and introducing it back into the tundra to combat climate change. Revive & Restore is a nonprofit in California that uses genome editing technologies to enhance conservation efforts in sometimes controversial ways.

Format: Articles

Subject: Theories, Technologies, Organizations, Ethics

A Series of YouTube Videos Detailing the “CRISPR Babies” Experiment (2018), by He Jiankui

In 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful human birth after genome editing had been performed on an embryo using CRISPR-cas9. CRISPR-cas9 is a genome editing tool derived from bacteria that can be used to cut out and replace specific sequences of DNA. He genetically modified embryos at his lab in Shenzhen, China, to make them immune to contracting HIV through indirect perinatal transmission from their father, who was infected with the virus.

Format: Articles

Subject: Publications, Experiments, Ethics

Sergio Cereceda Stone (1942- )

Sergio Cereceda Stone was born 16 April 1942 in the coastal city of Valparaiso, Chile. Stone's mother Luz was a housewife and caretaker for Sergio and his younger brother Lionel; his father Sergio served among the country's twenty appellate court judges. In the early 1950s Stone's father relocated the family to Santiago to further his law career.

Format: Articles

Subject: People, Ethics, Reproduction

Abortion

Abortion is the removal of the embryo or fetus from the womb, before birth can occur-either naturally or by induced labor. Prenatal development occurs in three stages: the zygote, or fertilized egg; the embryo, from post-conception to eight weeks; and the fetus, from eight weeks after conception until the baby is born. After abortion, the infant does not and cannot live. Spontaneous abortion is the loss of the infant naturally or accidentally, without the will of the mother. It is more commonly referred to as miscarriage.

Format: Articles

Subject: Processes, Ethics, Reproduction

Ethics of Designer Babies

A designer baby is a baby genetically engineered in vitro for specially selected traits, which can vary from lowered disease-risk to gender selection. Before the advent of genetic engineering and in vitro fertilization (IVF), designer babies were primarily a science fiction concept. However, the rapid advancement of technology before and after the turn of the twenty-first century makes designer babies an increasingly real possibility.

Format: Articles

Subject: Ethics, Reproduction

Eugenical Sterilization in the United States (1922), by Harry H. Laughlin

Eugenical Sterilization in the United States is a 1922 book in which author Harry H. Laughlin argues for the necessity of compulsory sterilization in the United States based on the principles of eugenics. The eugenics movement of the early twentieth century in the US focused on altering the genetic makeup of the US population by regulating immigration and sterilization, and by discouraging interracial procreation, then called miscegenation.

Format: Articles

Subject: Outreach, Legal, Ethics, Publications

The Singapore Bioethics Advisory Committee

Established in tandem with Singapore's national Biomedical Sciences Initiatives, the Bioethics Advisory Committee (BAC) was established by the Singapore Cabinet in December 2000 to examine the potential ethical, legal, and social issues arising from Singapore's biomedical research sector, and to recommend policy to Singapore's government.

Format: Articles

Subject: Organizations, Ethics, Legal

United States v. Georgia (2006)

In United States v. Georgia, the United States Supreme Court held, in a unanimous decision, that the rights protected under the Americans with Disabilities Act, or the ADA, extended to inmates held in state prisons. The Court also abolished sovereign immunity in cases where the Eighth Amendment is involved. The case came about as a result of Tony Goodman, a paraplegic man in a Georgia state prison, who attempted to sue the state under Title II of the ADA.

Format: Articles

Subject: Legal, Ethics, Disorders

Medical Vibrators for Treatment of Female Hysteria

During the late 1800s through the early 1900s, physicians administered pelvic massages involving clitoral stimulation by early electronic vibrators as treatments for what was called female hysteria. Until the early 1900s, physicians used female hysteria as a diagnosis for women who reported a wide range of complaints and symptoms unexplainable by any other diagnosis at the time. According to historian Rachel Maines, physicians provided pelvic massages for thousands of years to female patients without it being considered erotic or sexually stimulating.

Format: Articles

Subject: Reproduction, Technologies, Ethics

“The Science and Ethics of Making Part-Human Animals in Stem Cell Biology” (2006), by Jason Scott Robert

In 2006, bioethicist Jason Scott Robert published “The Science and Ethics of Making Part-Human Animals in Stem Cell Biology” in The FASEB Journal. There, he reviews the scientific and ethical justifications and restrictions on creating part-human animals. Robert describes part-human animals, otherwise known as chimeras, as those resulting from the intentional combination of human and nonhuman cells, tissues, or organs at any stage of development.

Format: Articles

Subject: Ethics, Publications, Organisms

Bowen v. Kendrick (1988)

On 29 June 1988, in Bowen v. Kendrick, the US Supreme Court ruled in a five-to-four decision that the 1981 Adolescent Family Life Act, or AFLA, was constitutional. Under AFLA, the US government could distribute federal funding for abstinence-only sexual education programs, oftentimes given to groups with religious affiliations. As a federal taxpayer, Chan Kendrick challenged the constitutionality of AFLA, claiming it violated the separation of church and state.

Format: Articles

Subject: Legal, Ethics, Outreach

National Association for Down Syndrome (1960–)

The National Association for Down Syndrome, or NADS, is an organization that was founded in 1960 by Kathryn McGee in Chicago, Illinois, to support people with Down syndrome and their families in improving their quality of life. Originally named the Mongoloid Developmental Council, NADS is one of the oldest organizations serving people with Down syndrome and their families in the United States. According to NADS, Down syndrome is a genetic condition that occurs in one in every seven hundred ninety-two people and that causes delays in physical and intellectual development.

Format: Articles

Subject: Disorders, Organizations, People, Ethics