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Robert Alan Good (1922-2003)

Robert Alan Good was an American physician and scientific researcher who explored the cellular mechanisms of immunity. His research and discoveries earned him the label of "father of modern immunology." Though his work in immunology is considered his greatest scientific achievement, Good is also well known for his work with tissue engineering. From his research on immunology, Good was able to perform the first successful allogeneic (donor and recipient are unrelated) bone marrow transplant.

Format: Articles

Subject: People

Min Chueh Chang (1908-1991)

As one of the researchers involved in the development of the oral contraceptive pill, Min Chueh Chang helped to revolutionize the birth control movement. Although best known for his involvement with "the pill," Chang also made a number of discoveries throughout his scientific career involving a range of topics within the field of reproductive biology. He published nearly 350 articles in scientific journals.

Format: Articles

Subject: People, Reproduction

Neonatal Jaundice

Neonatal jaundice is the yellow discoloration of the skin and eyes due to elevated bilirubin levels in the bloodstream of a newborn. Bilirubin is a byproduct of the breakdown of red blood cells. Jaundiced infants are unable to process bilirubin at a normal rate or they have an abnormally high amount of bilirubin in their bloodstream, resulting in a buildup of the yellow colored bilirubin. That build up is called hyperbilirubinemia and is the cause of jaundice.

Format: Articles

Subject: Disorders

“Miscarriage of Medicine: The Growth of Catholic Hospitals and the Threat to Reproductive Health Care” (2013), by Lois Uttley, Sheila Reynertson, Larraine Kenny, and Louise Melling

In 2013, Lois Uttley, Sheila Reynertson, Larraine Kenny, and Louise Melling published “Miscarriage of Medicine: The Growth of Catholic Hospitals and the Threat to Reproductive Health Care,” in which they analyzed the growth of Catholic hospitals in the United States from 2001 to 2011 and the impact those hospitals had on reproductive health care. In the US, Catholic hospitals are required to abide by the US Catholic Church's Ethical Guidelines for Health Care Providers, also called the Directives.

Format: Articles

Subject: Publications

Stem Cell Tourism

When James Thomson of the University of Wisconsin announced in 1998 that he had derived and cultured human embryonic stem cells(hESCs), Americans widely believed-and accepted-that stem cells would one day be the basis of a multitude of regenerative medical techniques. Researchers promised that they would soon be able to cure a variety of diseases and injuries such as cancer, diabetes, Parkinson's, spinal cord injuries, severe burns, and many others. But it wasn't until January 2009 that the Food and Drug Administration approved the first human clinical trials using hESCs.

Format: Articles

Subject: Theories, Ethics

Truman William Brophy (1848–1928)

Truman William Brophy developed a cleft palate surgical repair, later called the Brophy Operation, in the late nineteenth century US. The procedure improved facial aesthetics and speech in cleft palate patients. A cleft palate occurs during development when the palatal bones in the roof of the mouth don't completely fuse, leaving an opening, or cleft, in the upper lip and mouth. Brophy's cleft repair used compression inside and outside of the mouth to push the palatal bones into normal alignment shortly after birth.

Format: Articles

Subject: People, Disorders

Lynn Petra Alexander Sagan Margulis (1938-2011)

Lynn Petra Alexander Sagan Margulis was an American biologist, whose work in the mid-twentieth century focused on cells living together in a mutually advantageous relationship, studied cells and mitochondria in the US during the second half of the twentieth century. She developed a theory for the origin of eukaryotic cells, that proposed two kinds of structures found in eukaryotic cells mitochondria in animals, and plastids in plantsÑwere once free-living bacteria that lived harmoniously and in close proximity to larger cells, a scenario called symbiosis.

Format: Articles

Subject: People, Theories

Oviraptor philoceratops Dinosaurs

Oviraptor philoceratops was a small bird-like dinosaur that lived about seventy-five million years ago, during the late Cretaceous period. In 1923, George Olsen of the American Museum of Natural History (AMNH) in New York City, New York, discovered the first Oviraptor fossilized skeleton on top of a dinosaur egg nest in the Gobi Desert, Mongolia. Because of the close proximity of dinosaur and nest, when Henry Fairfield Osborn president of the AMNH published on the discovery, he assumed that the Oviraptor had died attempting to steal the eggs.

Format: Articles

Subject: Organisms

Jérôme Lejeune (1926−1994)

Jérôme Lejeune was a French physician and researcher who studied genetics and developmental disorders. According to the Jérôme Lejeune Foundation, in 1958, Lejeune discovered that the existence of an extra twenty-first chromosome, a condition called Trisomy 21, causes Down Syndrome. Down Syndrome is a condition present in an individual since birth and is characterized by physical and developmental anomalies such as small ears, a short neck, heart defects, and short height as children and adults.

Format: Articles

Subject: People

Elizabeth Blackwell (1821–1910)

In the nineteenth century, Elizabeth Blackwell was a women’s healthcare reformer and the first woman to receive her medical degree in the United States. She practiced medicine as a primary care physician in both the United States and the United Kingdom. Blackwell graduated medical school from Geneva Medical College in Geneva, New York, where she was the first woman to receive a medical degree in the US.

Format: Articles

Subject: People

Marshall Henry Klaus (1927–2017)

Marshall Henry Klaus was a scientist and pediatrician who studied maternal-infant bonding in the twentieth century in the United States. Maternal-infant bonding is the psychological and chemical attachment between mother and infant. Klaus cofounded DONA International, an organization that trains birthing aides, called doulas, to provide physical and emotional support to laboring mothers. He also studied the differences between the layouts and quality of care provided in nurseries and birthing centers in different countries and compared them to those found in the United States.

Format: Articles

Subject: People

“What Can We Do About Cancer? The Most Vital and Insistent Question in the Medical World” (1913), by Samuel Hopkins Adams

In 1913, journalist Samuel Hopkins Adams published “What Can We Do About Cancer? The Most Vital and Insistent Question in the Medical World,” hereafter “What Can We Do About Cancer,” in Ladies’ Home Journal. Cancer is a disease that is the result of abnormal cell division in different parts of the body, such as the breasts or the cervix. During that time, many women did not discuss or disclose early symptoms of reproductive cancers, such as breast lumps and abnormal vaginal discharge, out of shame or disgust. Thus, people often considered cancer to be a taboo topic.

Subject: Publications

Harry Hamilton Laughlin (1880-1943)

Harry Hamilton Laughlin helped lead the eugenics
movement in the United States during the early twentieth century.
The US eugenics movement of the early twentieth century sought to
reform the genetic composition of the United States population through
sterilization and other restrictive reproductive measures. Laughlin
worked as superintendent and assistant director of the Eugenics
Research Office (ERO) at Cold Spring Harbor Laboratory in Cold
Spring Harbor, New York, alongside director Charles Davenport.

Format: Articles

Subject: People, Reproduction

Stanley Cohen (1922- )

Stanley Cohen is a biochemist who participated in the discovery of nerve growth factor (NGF) and epidermal growth factor (EGF). He shared the 1986 Nobel Prize in Physiology or Medicine with Rita Levi-Montalcini for their work on the discovery of growth factors. His work led to the discovery of many other growth factors and their roles in development.

Format: Articles

Subject: People

Wilhelm August Oscar Hertwig (1849-1922)

Wilhelm August Oscar Hertwig contributed to embryology through his studies of cells in development and his discovery that only one spermatozoon is necessary to fertilize an egg. He was born 21 April 1849 to Elise Trapp and Carl Hertwig in Hessen, Germany. After his brother Richard was born the family moved to Muhlhausen in Thuringen where the boys were educated. The two brothers later attended the university in Jena from 1868 to 1888 and studied under Ernst Haeckel, who later convinced Hertwig to leave chemistry and pursue medicine.

Format: Articles

Subject: People

“Kangaroo Care Is Effective in Diminishing Pain Response in Preterm Neonates” (2003), by Celeste Johnston, Bonnie Stevens, Janet Pinelli, Sharyn Gibbins, Francoise Filion, Anne Jack, Susan Steele, Kristina Boyer, and Annie Veilleux

In the 2003 article “Kangaroo Care Is Effective in Diminishing Pain Response in Preterm Neonates”, Celeste Johnston, Bonnie Stevens, Janet Pinelli, and their colleagues evaluate the effectiveness of the Kangaroo Mother Care position in decreasing the pain response of preterm infants who undergo a heel lance procedure for blood collection. Kangaroo Mother Care is a method of treatment for premature and low birth weight infants that involves exclusive breastfeeding and skin-to-skin contact between a mother and her infant in what is called the kangaroo position.

Format: Articles

Subject: Publications

Walter Schiller (1887–1960)

Walter Schiller studied the causes of diseases in the US and Austria in the early twentieth century and in 1928, invented the Schiller test, or a way to diagnose early cervical cancer in women. Cervical cancer is the uncontrollable division of cells in the cervix, or lower part of the uterus. While living in Austria until his emigration to escape the Nazis in 1937, Schiller concluded that there was a form of cervical cancer, later named carcinoma in situ, that physicians could detect earlier than when tumors start to appear.

Format: Articles

Subject: People

Isidore Geoffroy Saint-Hilaire (1805-1861)

Isidore Geoffroy Saint-Hilaire studied anatomy and congenital abnormalities in humans and other animals in nineteenth century France. Under the tutelage of his father, Etienne Geoffroy Saint-Hilaire, Isidore compiled and built on his father's studies of individuals with developmental malformations, then called monstrosities.

Format: Articles

Subject: People, Disorders

“Labor and Delivery Outcomes among Young Adolescents” (2015), by Ana J. Torvie, Lisa S. Callegari, Melissa A. Schiff, Katherine E. Debiec

In July 2015, Ana J. Torvie, Lisa S. Callegari, Melissa A. Schiff, and Katherine E. Debiec published “Labor and Delivery Outcomes Among Young Adolescents,” hereafter “Labor and Delivery Outcomes,” in the American Journal for Obstetrics and Gynecology. The authors conducted a study using birth certificate data and hospital records in the state of Washington to compare the frequency and outcomes of cesarean and surgically assisted vaginal births among different age groups of pregnant people.

Format: Articles

Subject: Publications, Reproduction

"Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants" (2010), by Scott Sicherer, et al.

In 2010, a team of US researchers concluded that the more peanuts a pregnant woman ate during her pregnancy, the more likely her newborn was to be sensitive to peanuts. They published their results in 2010's "Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants." The work resulted from the collaboration of Scott Sicherer and Hugh Sampson, both from the Jaffe Food Allergy Institute, Mount Sinai School of Medicine, in New York, New York along with other colleagues.

Format: Articles

Subject: Experiments, Reproduction

Dysmenorrhea as a Menstrual Disorder

Dysmenorrhea refers to painful menstrual bleeding and often includes symptoms such as cramps in the lower abdominal region, pain radiating down to the thighs, nausea and vomiting, diarrhea, fatigue, and headaches. There are two types of dysmenorrhea, called primary and secondary dysmenorrhea, which develop in different ways. In cases of primary dysmenorrhea, people experience painful cramps before and during most of their menstrual cycles, which does not happen as a result of a different underlying condition and is mostly due to hormone imbalances.

Format: Articles

Subject: Disorders, Theories

"Purification of a Nerve-Growth Promoting Protein from the Mouse Salivary Gland and its Neuro-Cytoxic Antiserum" (1960), by Stanley Cohen

Stanley Cohen published "Purification of a Nerve-Growth Promoting Protein from the Mouse Salivary Gland and its Neuro-Cytoxic Antiserum" in the Proceedings of the National Academies of Sciences in 1960. This paper outlined the successful purification and identification of nerve growth factor (NGF) as a protein, the developmental effects of depriving an embryo of NGF, and the discovery that NGF is also required for the maintenance of the nervous system.

Format: Articles

Subject: Experiments

Bernard Sachs (1858-1944)

Bernard Sachs studied nervous system disorders in children in the
United States during the nineteenth and twentieth centuries. In the
late 1880s, Sachs described the fatal genetic neurological disorder
called amaurotic family idiocy, later renamed Tay-Sachs disease. The
disorder degrades motor skills as well as mental abilities in
affected individuals. The expected lifespan of a child with
Tay-Sachs is three to five years. In addition to working on
Tay-Sachs disease, Sachs described other childhood neurological and

Format: Articles

Subject: People

James Alexander Thomson (1958- )

James Alexander Thomson, affectionately known as Jamie Thomson, is an American developmental biologist whose pioneering work in isolating and culturing non-human primate and human embryonic stem cells has made him one of the most prominent scientists in stem cell research. While growing up in Oak Park, Illinois, Thomson's rocket-scientist uncle inspired him to pursue science as a career. Born on 20 December 1958, Thomson entered the nearby University of Illinois Urbana-Champaign nineteen years later as a National Merit Scholar majoring in biophysics.

Format: Articles

Subject: People

Virginia Apgar (1909–1974)

Virginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women’s pain during childbirth, in the US in the mid-twentieth century. In 1953, Apgar created a scoring system using five easily assessable measurements, including heart rate and breathing rate, to evaluate whether or not infants would benefit from medical attention immediately after birth. Apgar’s system showed that infants who were previously set aside as too sick to survive, despite low Apgar scores, could recover with immediate medical attention.

Format: Articles

Subject: People, Reproduction