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The extraembryonic membranes that surround and originate from the embryos of vertebrates such as birds, reptiles, and mammals are crucial to their…
AmniocentesisReproductionFetusMary Frances Lyon studied gene expression and developed the theory of X-chromosome inactivation, also called Lyonization, during the twentieth…
Gene ExpressionX Chromosome InactivationLyon HypothesisLyonizationMutationIn 1961, Mary Lyon, a researcher who studied genetics, published “Gene Action in the X-chromosome of the Mouse (Mus Musculus L.),” hereafter “Gene…
Sex ChromosomesChromosomes, Human, XX chromosomeGenes, X-linkedX Chromosome InactivationBy 2011, researchers in the US had established that non-invasive blood tests can accurately determine the gender of a human fetus as early as seven…
ContextDiagnostic sex determinationSex PreselectionFetusSex Determination AnalysisEndoscopic fetoscopy is a minimally invasive surgical procedure performed during pregnancy that allows physicians to view the fetus in-utero.…
TechnologyEndoscopyFetoscopyPrenatal DiagnosisTay-Sachs DiseaseAmniocentesis is a test used for prenatal diagnosis of inherited diseases, Rh incompatibility, neural tube defects, and lung maturity. Normally…
AmniocentesisReproductionFetusWhen James Thomson of the University of Wisconsin announced in 1998 that he had derived and cultured human embryonic stem cells(hESCs), Americans…
Stem CellsethicsAndrew Zachary Fire is a professor at Stanford University and Nobel Laureate. Fire worked at the Carnegie Institution of Washington's Department of…
PeopleRNA InterferenceBiographyIn 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful…
Literaturegene editingGenome EditingCRISPR (Genetics)CRISPR-associated protein 9Among other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblasts