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"Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (2007), by Junying Yu et al.
By: Ke Wu
| Published: Jun 29, 2010
On 2 December 2007, Science published a report on creating human induced pluripotent stem (iPS) cells from human somatic cells: "Induced Pluripotent…
LiteratureStem CellsPublicationsSomatic cells
“Human Acute Myeloid Leukemia Is Organized as a Hierarchy That Originates from a Primitive Hematopoietic Cell” (1997), by Dominique Bonnet and John E. Dick
By: Akaash Surendra
| Published: Aug 08, 2025
In the 1990s, John E. Dick and Dominique Bonnet, researchers at the University of Toronto, in Toronto, Ontario, investigated how a blood cancer…
Leukemia, Myeloid, AcuteStem Cell ResearchAcute myeloid leukemiaStem CellsCarcinogenesis
"Genetic Evidence Equating SRY and the Testis-Determining Factor" (1990), by Phillippe Berta et al.
By: Troy Cox
| Published: Jan 10, 2014
In the late 1980s, Peter Goodfellow in London, UK led a team of researchers who showed that the SRY gene in humans codes a protein that causes testes…
TestisY ChromosomeEmbryosChromosomesSex Chromosomes
Stem Cells
By: Ke Wu
| Published: Oct 29, 2010
According to the US National Institutes of Health (NIH), the standard American source on stem cell research, three characteristics of stem cells…
Stem Cells
Anencephaly
By: Jesse King
| Published: Feb 13, 2013
Anencephaly is an open neural tube defect, meaning that part of the neural tube does not properly close or that it has reopened during early…
fetal developmentFetus--AbnormalitiesBirth DefectsEmbryologyPregnancy
Alejandro Sánchez Alvarado (1964- )
By: Mary E. Sunderland
| Published: Jun 10, 2010
Alejandro Sánchez Alvarado is a Professor of Neurobiology and Anatomy at the University of Utah School of Medicine and is also a Howard Hughes…
PeopleSánchez Alvarado, AlejandroRegenerationBiography
The Role of the Notch signaling pathway in Somitogenesis
By: Justin M. Wolter
| Published: Mar 23, 2014
Among other functions, the Notch signaling pathway contributes to the development of somites in animals. It involves a cell signaling mechanism with…
Notch genesNotch ProteinsReceptors, NotchNotch Receptors
China's First Baby Conceived through In Vitro Fertilization-Embryonic Transfer, by Zhang Lizhu's Research Team
By: Lijing Jiang
| Published: Apr 27, 2011
On 10 March 1988, China's first baby conceived through human in vitro fertilization (IVF) and embryo transfer (ET), commonly referred to as a test-…
ReproductionExperimentsFertility
Stanley Paul Leibo (1937–2014)
By: Risa Aria Schnebly
| Published: Feb 05, 2021
Stanley Paul Leibo studied the cryopreservation of embryos in the US in the twentieth century. Cryopreservation is a method of preserving biological…
Low temperature engineeringCryonicsScience and civilizationEmbryo transplantationCryotherapy
Digit Regeneration Is Regulated by Msx1 and BMP4 in Fetal Mice (2003), by Manjong Han et al.
By: Joe Brinkman
| Published: Apr 13, 2015
In the early 2000s, Manjong Han, Xiaodang Yang, Jennifer Farrington, and Ken Muneoka investigated how genes and proteins in fetal mice (Mus musculus…
Regeneration (Biology)MiceRegenerationHomeobox genesBone Morphogenetic Proteins