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A Series of YouTube Videos Detailing the “CRISPR Babies” Experiment (2018), by He Jiankui
By: Risa Aria Schnebly, Brianna Ellis
| Published: Jul 31, 2021
In 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful…
Literaturegene editingGenome EditingCRISPR (Genetics)CRISPR-associated protein 9
"Programmed Cell Death-II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (1964), by Richard A. Lockshin and Carroll M. Williams
By: Lijing Jiang
| Published: Apr 27, 2011
Richard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormones
Gene Transfer Strategy Used to Treat Tay - Sachs Disease (2005), by Sabata Martino’s Research Group
By: Tiffany Nardi
| Published: Feb 21, 2017
In the early 2000s, Sabata Martino and a team of researchers in Italy and Germany showed that they could reduce the symptoms of Tay-Sachs in…
Tay-Sachs DiseaseVirus-vector relationshipsGloboid Cell LeukodystrophyGangliosidesGene Therapy
Jeffrey Weinzweig's Experiments on In Utero Cleft Palate Repair in Goats (1999-2002)
By: Jillian R. Kersten
| Published: Apr 07, 2017
Jeffrey Weinzweig and his team, in the US at the turn of the twenty-first century, performed a series of experiments on fetal goats to study the…
Fetus--SurgeryFetal growth disordersDiseases--Animal modelsAnimal models in researchGoats
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007
By: Zane Bartlett
| Published: Jun 01, 2015
In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental Biology