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Interspecies SCNT-derived Humanesque Blastocysts
By: Sarah Taddeo, Jason S. Robert, Nicole Diehnelt
| Published: Jun 23, 2017
Since the 1950s, scientists have developed interspecies blastocysts in laboratory settings, but not until the 1990s did proposals emerge to engineer…
BlastocystDiseasesbioethicsTadpoleCell nuclei--Transplantation
The Process of Implantation of Embryos in Primates
By: Justin M. Wolter
| Published: Mar 21, 2013
Implantation is a process in which a developing embryo, moving as a blastocyst through a uterus, makes contact with the uterine wall and remains…
FetusPregnancyEmbryologyDevelopmental BiologyEmbryos
Thesis: Growing Human Organs in Animals: Interspecies Blastocyst Complementation as a Potential Solution for Organ Transplant Limitations
By: Alexis Darby
| Published: Mar 08, 2021
To address the progression of immune-related constraints on organ transplantation, the first part of this thesis contains a historical analysis…
organ transplantationOrgan TransplantsTransplant RecipientsTransplant Recipient
Human Embryonic Stem Cells
By: Ke Wu
| Published: Sep 13, 2010
Stem cells are undifferentiated cells that are capable of dividing for long periods of time and can give rise to specialized cells under particular…
Stem CellsReproductiondifferentiationHuman Development
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
"Sheep Cloned by Nuclear Transfer from a Cultured Cell Line" (1996), by Keith Campbell, Jim McWhir, William Ritchie, and Ian Wilmut
By: Zane Bartlett
| Published: Sep 19, 2014
In 1995 and 1996, researchers at the Roslin Institute in Edinburgh, Scotland, cloned mammals for the first time. Keith Campbell, Jim McWhir, William…
CloningClone CellsCloning, MolecularCloning, OrganismExperiments
"Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli" (1980), by Janet Rossant and William I. Frels
By: Nicole Newkirk
| Published: Oct 30, 2007
In 1980 Janet Rossant and William I. Frels published their paper, "Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between…
ChimeraExperimentsMice
"Experimental Chimeras' Removal of Reproductive Barrier Between Sheep and Goat" (1984), by Sabine Meinecke-Tillmann and Burkhard Meinecke
By: Nicole Newkirk
| Published: Feb 28, 2008
In 1984 Sabine Meinecke-Tillmann and Burkhard Meinecke published their article "Experimental Chimeras - Removal of Reproductive Barrier Between Sheep…
ChimeraExperimentsSheepGoats
Karl Oskar Illmensee (1939–)
By: Cheryl Lancaster
| Published: Feb 26, 2017
Karl Oskar Illmensee studied the cloning and reproduction of fruit flies, mice, and humans in the US and Europe during the twentieth and twenty-first…
CloningMolecular CloningClone CellsTwinsEmbryos
"Embryonic Stem Cell Lines Derived from Human Blastocytes" (1998), by James Thomson
By: Ke Wu
| Published: Feb 01, 2011
After becoming chief pathologist at the University of Wisconsin-Madison Wisconsin Regional Primate Center in 1995, James A. Thomson began his…
Stem CellsExperimentsPublicationsHuman Development