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Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007
By: Zane Bartlett
| Published: Jun 01, 2015
In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental Biology
Amphioxus, and the Mosaic Theory of Development (1893), by Edmund Beecher Wilson
By: James Lowe
| Published: Mar 31, 2015
Edmund Beecher Wilson experimented with Amphioxus (Branchiostoma) embryos in 1892 to identify what caused their cells to differentiate into new types…
Wilson, Edmund B. (Edmund Beecher), 1856-1939AmphioxusEmbryosEmbryologyDevelopmental Biology
"The Cell-Theory" (1853), by Thomas Henry Huxley
By: Samantha Hauserman
| Published: Dec 12, 2013
The Cell-Theory was written by Thomas Henry Huxley in Britain and published in 1853 by The British and Foreign Medico-Chirurgical Review. The twenty-…
LiteratureEpigeneticsEmbryologyHuxley, Thomas Henry, 1825-1895Cellular control mechanisms
"Gene Regulation for Higher Cells: A Theory" (1969), by Roy J. Britten and Eric H. Davidson
By: Justin Wolter
| Published: Sep 10, 2013
In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenes
The Role of the Notch Signaling Pathway in Myogenesis
By: Justin M. Wolter
| Published: Jul 26, 2013
Among other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblasts
"The Inductive Capacity of Oral Mesenchyme and Its Role in Tooth Development" (1969-1970), by Edward J. Kollar and Grace R. Baird
By: Kate MacCord
| Published: Mar 15, 2013
Between February 1969 and August 1970 Edward Kollar and Grace Baird, from the University of Chicago in Chicago, Illinois, published three papers that…
teethEmbryosCell differentiationMesenchymeEpithelium
The Notch Signaling Pathway in Embryogenesis
By: Justin Wolter
| Published: Mar 06, 2013
The Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genes
"On the Induction of Embryonic Primordia by Implantation of Organizers from Different Species" (1924), Hilde Mangold's Dissertation
By: Megan Kearl, Kate MacCord
| Published: Dec 19, 2012
Hilde Proscholdt Mangold was a doctoral student at the Zoological Institute at the University of Freiburg in Freiburg, Germany, from 1920-1923.…
LiteratureEmbryosTrembley, Abraham, 1710-1784GastrulationEmbryology
Epithelium
By: Kate MacCord
| Published: Oct 17, 2012
Frederik Ruysch, working in the Netherlands, introduced the term epithelia in the third volume of his Thesaurus Anatomicus in 1703. Ruysch created…
EpitheliumRuysch, Frederik, 1638-1731AnatomyCells--MorphologyHis, Wilhelm, 1831-1904
Spemann-Mangold Organizer
By: Samuel Philbrick, Erica O'Neil
| Published: Jan 12, 2012
The Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulation