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Frederik Ruysch, working in the Netherlands, introduced the term epithelia in the third volume of his Thesaurus Anatomicus in 1703. Ruysch created…
EpitheliumRuysch, Frederik, 1638-1731AnatomyCells--MorphologyHis, Wilhelm, 1831-1904As mice embryos develop, they undergo a stage of development called gastrulation. The hallmark of vertebrate gastrulation is the reorganization of…
GastrulationMiceGerm CellsSomatic embryogenesisEmbryosMesenchyme is a type of animal tissue comprised of loose cells embedded in a mesh of proteins and fluid, called the extracellular matrix. The loose,…
MesenchymeGastrulationStem CellsMesenchymal Stem CellsEmbryologyThe source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across…
Crick, Francis, 1916-2004Nobel Prize winnersEmbryosMorphogenesisGenesThe Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulationThe epigenetic landscape is a concept representing embryonic development. It was proposed by Conrad Hal Waddington to illustrate the various…
Waddington, C. H. (Conrad Hal), 1905-1975EpigeneticsCell differentiationEmbryologyDevelopmental BiologyConrad Hal Waddington's "Experiments on Embryonic Induction III," published in 1934 in the Journal of Experimental Biology, describes the discovery…
Waddington, C. H. (Conrad Hal), 1905-1975EmbryosCell differentiationEmbryologyChickens--EmbryosResearch in chemical induction seeks to identify the compound or compounds responsible for differentiation in a developing embryo. Soren Lovtrup…
Cell differentiationEmbryosDevelopmental BiologyNotochordWaddington, C. H. (Conrad Hal), 1905-1975In this paper Viktor Hamburger and Rita Levi-Montalcini collaborated to examine the effects of limb transplantation and explantation on neural…
Chickens--EmbryosDevelopmental BiologyCell differentiationEmbryosLevi-Montalcini, Rita