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Johannes Holtfreter made important discoveries about the properties of the organizer discovered by Hans Spemann. Although he spent much time away…
Organizers, EmbryonicBiographyFrogsGeorge Herbert Hitchings researched and developed medications that targeted specific parts of DNA replication processes to treat cancers and various…
Nucleoside analogDNA ReplicationDrug DevelopmentAcyclovirPharmacologyJacques Loeb developed procedures to make embryos from unfertilized sea urchin eggs in 1899. Loeb called the procedures "artificial parthenogenesis…
ParthenogenesisExperimentsSea UrchinsNerve growth factor (NGF) is a signaling protein and growth factor implicated in a wide range of development and maintenance functions. NGF was…
Nerve Growth FactorChicksNational Geographic's documentary In the Womb: Identical Twins focuses on the prenatal development of human identical twins. Director Lorne Townend…
LiteratureTwinsDocumentary filmsTestosteroneMethylationWilhelm Roux was a nineteenth-century experimental embryologist who was best known for pioneering Entwicklungsmechanik, or developmental mechanics.…
PeopleRoux, Wilhelm, 1850-1924BiographyShoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial DiseasesWhen cells-but not DNA-from two or more genetically distinct individuals combine to form a new individual, the result is called a chimera. Though…
ContextChimerismEmbryosEmbryonic Stem CellsMosaicismTooth enamel contains relics of its formation process, in the form of microstructures, which indicate the incremental way in which it forms. These…
EvolutionteethDental EnamelHuman EvolutionAnatomyChristiane Nusslein-Volhard studied how genes control embryonic development in flies and in fish in Europe during the twentieth and twenty-first…
DrosophilaEmbryologyGenesMorphogenesisRNA polymerases