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Teratogens are substances that may produce physical or functional defects in the human embryo or fetus after the pregnant woman is exposed to the…
Abnormalities, HumanFetusPregnancyTeratogenicity testingEmbryosVitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agentsThalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomideJosef Warkany studied the environmental causes of birth defects in the United States in the twentieth century. Warkany was one of the first…
Abnormalities, HumanVitamin ARetinoidsHypervitaminosiscalomelThe article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformationsSidney Q. Cohlan studied birth defects in the US during the twentieth century. Cohlan helped to discover that if a pregnant woman ate too much…
Abnormalities, HumanRetinoidsVitamin AHypervitaminosisTetracyclineIsotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogens