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US Regulatory Response to Thalidomide (1950-2000)
By: Chanapa Tantibanchachai
| Published: Apr 01, 2014
Thalidomide, a drug capable of causing fetal abnormalities (teratogen), has caused greater than ten thousand birth defects worldwide since its…
ContextThalidomideThalidomide--Side effectsTeratogenicity testingMultiple Myeloma
Studies of Thalidomide's Effects on Rodent Embryos from 1962-2008
By: Joanna Yang, Chanapa Tantibanchachai
| Published: Mar 07, 2014
Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomide
Retinoids As Teratogens
By: Chanapa Tantibanchachai
| Published: Feb 28, 2014
Vitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agents
Teratogens
By: Chanapa Tantibanchachai
| Published: Jan 22, 2014
Teratogens are substances that may produce physical or functional defects in the human embryo or fetus after the pregnant woman is exposed to the…
Abnormalities, HumanFetusPregnancyTeratogenicity testingEmbryos