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Sidney Q. Cohlan (1915-1999)
By: Bianca Zietal, Chanapa Tantibanchachai
| Published: Jun 18, 2017
Sidney Q. Cohlan studied birth defects in the US during the twentieth century. Cohlan helped to discover that if a pregnant woman ate too much…
Abnormalities, HumanRetinoidsVitamin AHypervitaminosisTetracycline
"Experimental Studies on Congenital Malformations" (1959), by James G. Wilson
By: Chanapa Tantibanchachai
| Published: Jun 15, 2017
The article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformations
Josef Warkany (1902–1992)
By: Chanapa Tantibanchachai, Bianca Zietal
| Published: May 26, 2017
Josef Warkany studied the environmental causes of birth defects in the United States in the twentieth century. Warkany was one of the first…
Abnormalities, HumanVitamin ARetinoidsHypervitaminosiscalomel
Whitner v. South Carolina (1997)
By: Chanapa Tantibanchachai
| Published: Nov 30, 2014
In the case Whitner v. South Carolina in 1997, the South Carolina State Supreme Court defined the concept of a child to include viable fetuses. This…
LawEmbryosReproductive RightsPregnancyAbortion
Isotretinoin (Accutane) as a Teratogen
By: Chanapa Tantibanchachai
| Published: Jul 20, 2014
Isotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogens
US Regulatory Response to Thalidomide (1950-2000)
By: Chanapa Tantibanchachai
| Published: Apr 01, 2014
Thalidomide, a drug capable of causing fetal abnormalities (teratogen), has caused greater than ten thousand birth defects worldwide since its…
ContextThalidomideThalidomide--Side effectsTeratogenicity testingMultiple Myeloma
Studies of Thalidomide's Effects on Rodent Embryos from 1962-2008
By: Joanna Yang, Chanapa Tantibanchachai
| Published: Mar 07, 2014
Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomide
Retinoids As Teratogens
By: Chanapa Tantibanchachai
| Published: Feb 28, 2014
Vitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agents
Teratogens
By: Chanapa Tantibanchachai
| Published: Jan 22, 2014
Teratogens are substances that may produce physical or functional defects in the human embryo or fetus after the pregnant woman is exposed to the…
Abnormalities, HumanFetusPregnancyTeratogenicity testingEmbryos
Ferguson v. City of Charleston (2001)
By: Chanapa Tantibanchachai
| Published: Nov 26, 2013
The US Supreme Court case Ferguson v. City of Charleston (2001) established that public hospitals couldn't legally drug test pregnant women without…
LawReproductive RightsPregnancyEmbryosDrug testing