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Estrogen plays a key role in the regulation of gene transcription. This is accomplished by its ability to act as a ligand and to bind to specific…
DiethylstilbestrolEstrogenHuman DevelopmentBisphenol A (BPA) is an organic compound that was first synthesized by Aleksandr Dianin, a Russian chemist from St. Petersburg, in 1891. The chemical…
bisphenol AReproductionHormonesHuman DevelopmentIn the US, one in 1000 births is affected by neural tube defects (NTD). A neural tube defect is a birth defect involving the malformation of body…
Neural Tube DefectsReproductionCongenital DisordersHuman DevelopmentIntroduced by Conrad Hal Waddington in 1942, the concept of epigenetics gave scientists a new paradigm of thought concerning embryonic development,…
EpigenomicsEpigeneticsIn 1914 Albert Niemann, a German pediatrician who primarily studied infant metabolism, published a description of an Ashkenazi Jewish infant with…
Niemann-Pick DiseasesHuman DevelopmentCongenital DisordersEmbryogenesis is an intricate process that can easily be disrupted by means of teratogenic agents. Some of these agents target the embryonic period's…
ThalidomideHuman DevelopmentFetus