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Robert Geoffrey Edwards's Study of in vitro Mammalian Oocyte Maturation, 1960 to 1965
By: Lijing Jiang
| Published: Aug 18, 2014
In a series of experiments between 1960 and 1965, Robert Geoffrey Edwards discovered how to make mammalian egg cells, or oocytes, mature outside of a…
Edwards, R. G. (Robert Geoffrey), 1925-2013Fertilization in VitroIn Vitro Oocyte Maturation TechniquesOocytesLuteinizing Hormone
"Cellular death in morphogenesis of the avian wing" (1962), by John W. Saunders Jr., et al.
By: Lijing Jiang
| Published: Mar 07, 2014
In the early 1960s, John W. Saunders Jr., Mary T. Gasseling, and Lilyan C. Saunders in the US investigated how cells die in the developing limbs of…
Cell DeathChickens--EmbryosApoptosisExperiments
Alexis Carrel's Immortal Chick Heart Tissue Cultures (1912-1946)
By: Lijing Jiang
| Published: Jul 03, 2012
In an effort to develop tissue culture techniques for long-term tissue cultivation, French surgeon and biologist Alexis Carrel, and his associates,…
Carrel, Alexis, 1873-1944Tissue cultureCellsGerm CellsEmbryos
"On the Permanent Life of Tissues outside of the Organism" (1912), by Alexis Carrel
By: Lijing Jiang
| Published: May 06, 2012
'On the Permanent Life of Tissues outside of the Organism' reports Alexis Carrel's 1912 experiments on the maintenance of tissue in culture media. At…
Tissue cultureStem CellsStem cells--ResearchEmbryologyGerm Cells
Robert Geoffrey Edwards and Patrick Christopher Steptoe's Clinical Research in Human in vitro Fertilization and Embryo Transfer, 1969-1980
By: Lijing Jiang
| Published: May 12, 2011
The biomedical accomplishment of human in vitro fertilization and embryo transfer (IVF-ET) took years to become the successful technique that…
ReproductionExperimentsFertilization
"Programmed Cell Death-II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (1964), by Richard A. Lockshin and Carroll M. Williams
By: Lijing Jiang
| Published: Apr 27, 2011
Richard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormones
China's First Baby Conceived through In Vitro Fertilization-Embryonic Transfer, by Zhang Lizhu's Research Team
By: Lijing Jiang
| Published: Apr 27, 2011
On 10 March 1988, China's first baby conceived through human in vitro fertilization (IVF) and embryo transfer (ET), commonly referred to as a test-…
ReproductionExperimentsFertility
Robert Geoffrey Edwards's Study of Fertilization of Human Oocytes Matured in vitro, 1965 to 1969
By: Lijing Jiang
| Published: Mar 10, 2011
Robert Geoffrey Edwards, a British developmental biologist at University of Cambridge, began exploring human in vitro fertilization (IVF) as a way to…
Fertilization in VitroExperimentsReproductionFertilizationOocytes
The Discovery of p53 Protein
By: Lijing Jiang
| Published: Jan 21, 2011
The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell Death
"The Effects of Wing Bud Extirpation on the Development of the Central Nervous System in Chick Embryos" (1934), by Viktor Hamburger
By: Lijing Jiang
| Published: Nov 22, 2010
German embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicks