periods (menstruation)

Lydia Pinkham’s Vegetable Compound (1873-1906)

Lydia Pinkham’s Vegetable Compound (1873-1906)

First marketed in the US 1875, Lydia Pinkham’s Vegetable Compound was an herbal medicine used by women to relieve menstrual discomfort and menopausal symptoms in women. The herbal compound was invented by Lydia Estes Pinkham in 1873 in her home kitchen in Lynn, Massachusetts. Pinkham created the compound by mixing alcohol with roots and herbs. The compound was patented, packaged, and distributed by the Mrs. Lydia Pinkham Medicine Company in 1876.

Clinical Tests of Estrogen Injections on Women with Abnormal Menstrual Cycles During the Early 1920s by Jean Paul Pratt and Edgar Allen

Clinical Tests of Estrogen Injections on Women with Abnormal Menstrual Cycles During the Early 1920s by Jean Paul Pratt and Edgar Allen

In the early twentieth century US, Jean Paul Pratt and Edgar Allen showed that if doctors injected estrogen into women with abnormal menstrual cycles, the cycles would become more normal. During clinical tests, researchers injected

Lydia Estes Pinkham (1819–1883)

Lydia Estes Pinkham (1819–1883)

Lydia Estes Pinkham invented and sold Lydia Pinkham’s Vegetable Compound, a medicinal tonic used to treat menstrual discomfort and promote female reproductive health in general, in the US during the nineteenth century. Pinkham also founded Mrs. Lydia E. Pinkham Medicine Company, a business that sold natural remedies for women’s health issues.

"The Premenstrual Syndrome" (1953), by Raymond Greene and Katharina Dalton

"The Premenstrual Syndrome" (1953), by Raymond Greene and Katharina Dalton

In 1953, Raymond Greene and Katharina Dalton, who were doctors in the UK, published "The Premenstrual Syndrome" in the British Medical Journal. In their article, Dalton and Greene established the term premenstrual syndrome (PMS). The authors defined PMS as a cluster of symptoms that include bloating, breast pain, migraine-headache, fatigue, anxiety, depression, and

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