His, Wilhelm, 1831-1904

Endothelium

Endothelium

The endothelium is the layer of cells lining the blood vessels in animals. It weighs more than one kilogram in adult humans, and it covers a surface area of 4000 to 7000 square meters. The endothelium is the cellular interface between the circulating blood and underlying tissue. As the medium between these two sets of tissues, endothelium is part of many normal and disease processes throughout the body.

Germ Layers

Germ Layers

A germ layer is a group of cells in an embryo that interact with each other as the embryo develops and contribute to the formation of all organs and tissues. All animals, except perhaps sponges, form two or three germ layers.

Ectoderm

Ectoderm

Ectoderm is one of three germ layers—groups of cells that coalesce early during the embryonic life of all animals except maybe sponges, and from which organs and tissues form. As an embryo develops, a single fertilized cell progresses through multiple rounds of cell division.

Endoderm

Endoderm

Endoderm is one of the germ layers—aggregates of cells that organize early during embryonic life and from which all organs and tissues develop. All animals, with the exception of sponges, form either two or three germ layers through a process known as gastrulation.

Epithelium

Epithelium

Frederik Ruysch, working in the Netherlands, introduced the term epithelia in the third volume of his Thesaurus Anatomicus in 1703. Ruysch created the term from the Greek epi, which means on top of, and thele, which means nipple, to describe the type of tissue he found when dissecting the lip of a cadaver.

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