Endocrinology

Diethylstilbestrol (DES) in the US

Diethylstilbestrol (DES) in the US

Diethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant women to prevent miscarriages, and later as an emergency contraceptive pill and to treat breast cancer. However, in 1971, physicians showed a link between DES and vaginal cancer during puberty in the children of women who had taken DES while pregnant.

William Withey Gull (1816-1890)

William Withey Gull (1816-1890)

William Withey Gull studied paraplegia, anorexia, and hormones as a physician in England during the nineteenth century. In addition to caring for patients, he described the role of the posterior column of the spinal cord in paraplegia, and he was among the first to describe the conditions of anorexia and of hypochondria.

Clinical Tests of Estrogen Injections on Women with Abnormal Menstrual Cycles During the Early 1920s by Jean Paul Pratt and Edgar Allen

Clinical Tests of Estrogen Injections on Women with Abnormal Menstrual Cycles During the Early 1920s by Jean Paul Pratt and Edgar Allen

In the early twentieth century US, Jean Paul Pratt and Edgar Allen showed that if doctors injected estrogen into women with abnormal menstrual cycles, the cycles would become more normal. During clinical tests, researchers injected

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