Cold Spring Harbor Laboratory

The Debate over DNA Replication Before the Meselson-Stahl Experiment (1953–1957)

The Debate over DNA Replication Before the Meselson-Stahl <a href="/search?text=Experiment" title="" class="lexicon-term">Experiment</a> (1953–1957)

Between 1953 and 1957, before the Meselson-Stahl experiment verified semi-conservative replication of DNA, scientists debated how DNA replicated. In 1953, James Watson and Francis Crick proposed that DNA

David Baltimore (1938– )

David Baltimore (1938– )

David Baltimore studied viruses and the immune system in the US during the twentieth century. In 1975, Baltimore was awarded the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, the enzyme used to transfer information from RNA to DNA. The discovery of reverse transcriptase contradicted the central dogma of biology at the time, which stated that the transfer of information was unidirectional from DNA, RNA, to protein. Baltimore’s research on

Barbara McClintock's Transposon Experiments in Maize (1931–1951)

Barbara McClintock's Transposon Experiments in Maize (1931–1951)

Barbara McClintock conducted experiments on corn (Zea mays) in the United States in the mid-twentieth century to study the structure and function of the chromosomes in the cells. McClintock researched how genes combined in corn and proposed mechanisms for how those interactions are regulated.

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