Publications

"The Cell-Theory" (1853), by Thomas Henry Huxley

By Samantha Hauserman

The Cell-Theory was written by Thomas Henry Huxley in Britain and published in 1853 by The British and Foreign Medico-Chirurgical Review. The twenty-two page article reviews twelve works on cell theory, including those in Germany by Caspar Friedrich Wolff in the eighteenth century and by Karl Ernst von Baer in the nineteenth century. Huxley spends much of The Cell-Theory on a cell theory proposed in the late 1830s by Matthias Schleiden and Theodor Schwann in Germany.

Created 2013-12-12

Last modified 2 years 2 months ago

Format: Articles

"Congenital Cataract following German Measles in the Mother" (1941), by Norman McAlister Gregg

By Lindsey O'Connell

In Australia in the 1940s, Norman McAlister Gregg observed a connection between pregnant women who contracted the rubella virus, or German measles, and cataract formation in their children's eyes. Gregg published his findings in the 1941 article Congenital Cataract following German Measles in the Mother in Transactions of the Ophthalmological Society of Australia. In the article, Gregg analyzed seventy-eight cases of congenital cataracts and suggested that the mothers' environmental factors could cause birth defects, otherwise known as teratogenic effects.

Created 2013-12-31

Last modified 2 years 3 months ago

Format: Articles

"Screening for Congenital Hypothyroidism" (1991), by Delbert A. Fisher

By Jennifer R. Craer

In his 1991 article Screening for Congenital Hypothyroidism, Delbert A. Fisher in the US reported on the implementation and impact of mass neonatal screening programs for congenital hypothyroidism (CH) from the early 1970s through 1991. CH is a condition that causes stunted mental and physical development in newborns unless treatment begins within the first three months of the newborn's life. In the early 1970s, regions in Canada and the US had implemented screening programs to diagnose and treat CH as quickly as possible after the infant's birth.

Created 2013-12-31

Last modified 2 years 2 months ago

Format: Articles

"Developmental Effects of Endocrine-Disrupting Chemicals in Wildlife and Humans" (1993), by Theo Colborn, Frederick S. vom Saal, and Ana M. Soto

By Jennifer R. Craer

Developmental Effects of Endocrine-Disrupting Chemicals in Wildlife and Humans, was published in 1993 in Environmental Health Perspectives. In the article, the authors present an account of two decades' worth of scientific research that describes the effects of certain pollutants on the health of wildlife, domestic animals, and humans, particularly when exposure takes place during embryonic growth. The term endocrine disruptor was coined in the article to describe the chemical pollutants that target the development and function of the endocrine system.

Created 2014-01-10

Last modified 2 years 3 months ago

Format: Articles

Studies in Spermatogenesis (1905), by Nettie Maria Stevens

By Troy Cox

Studies in Spermatogenesis is a two volume book written by Nettie Maria Stevens, and published by the Carnegie Institution of Washington in 1905 and 1906. In the books Stevens explains the research she conducted on chromosomal sex determination in the sperm and egg cells of insect species while at Bryn Mawr College, near Philadelphia, Pennsylvania. Studies in Spermatogenesis described early examples of chromosomal XY sex-determination.

Created 2014-01-22

Last modified 2 years 3 months ago

Format: Articles

"The Development of the Pronephros during the Embryonic and Early Larval Life of the Catfish (Ictalurus punctatus)" (1932), by Rachel L. Carson

By Karen Wellner

Rachel L. Carson studied biology at Johns Hopkins University in Maryland and graduated in 1933 with an MA upon the completion of her thesis, The Development of the Pronephros during the Embryonic and Early Larval Life of the Catfish (Ictalurus punctatus). The research that Carson conducted for this thesis project grounded many of the claims and observations she presented in her 1962 book, Silent Spring.

Created 2014-02-28

Last modified 2 years 3 months ago

Format: Articles

Hermaphrodites and the Medical Invention of Sex (1998), by Alice Domurat Dreger

By Mary Drago

Hermaphrodites and the Medical Invention of Sex, by historian of science Alice Domurat Dreger, was published in 1998 by Harvard University Press. In the book, Dreger describes how many doctors and scientists treated human hermaphrodites from the late nineteenth century to the early twentieth century. She states that during this time period, many physicians and scientists struggled to determine the nature sex, and to support a classification of sex as male or female, many physicians and scientists resorted to viewing a person's gonads for identification of his or her sex.

Created 2014-04-09

Last modified 5 months 3 weeks ago

Format: Articles

"On the Origin of Mitosing Cells" (1967), by Lynn Sagan

By Dorothy Regan Haskett

On the Origin of Mitosing Cells by Lynn Sagan appeared in the March 1967 edition of the Journal of Theoretical Biology. At the time the article was published, Lynn Sagan had divorced astronomer Carl Sagan, but kept his last name. Later, she remarried and changed her name to Lynn Margulis, and will be referred to as such throughout this article. In her 1967 article, Margulis develops a theory for the origin of complex cells that have enclosed nuclei, called eukaryotic cells.

Created 2014-04-15

Last modified 2 years 11 months ago

Format: Articles

Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore

By Mary Drago

In 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones, which was published in the same year as a first-edition monograph. In the book, Moore argues that regulation of sex differentiation in mammals is not controlled by sex hormones secreted by embryonic sex organs (gonads), but is controlled by non-hormonal genetic factors.

Created 2014-05-03

Last modified 2 years 10 months ago

Format: Articles

"Autistic Disturbances of Affective Contact" (1943), by Leo Kanner

By Sean Cohmer

Leo Kanner published Autistic Disturbances of Affective Contact in 1943 in the journal Nervous Child. This article described the cases of eleven children with autism. Kanner described the behavior and upbringing of each child, aged two to eight, as well as the educational backgrounds of the children's.

Created 2014-05-23

Last modified 2 years 10 months ago

Format: Articles

Infantile Autism: The Syndrome and Its Implications for a Neural Theory of Behavior (1964), by Bernard Rimland

By Sean Cohmer

Infantile Autism: The Syndrome and Its Implications for a Neural Theory of Behavior (hereafter Infantile Autism) is a book written by Bernard Rimland, published in 1964. The book proposed a theory to explain the causes of autism. The book also synthesized research into autism and used Rimland's neural theory, described in the book, as a theory to explain some aspects of behavior, intelligence, and abnormality.

Created 2014-05-23

Last modified 2 years 1 month ago

Format: Articles

Environment and Birth Defects (1973), by James G. Wilson

By S. Alexandra Aston

Environment and Birth Defects by James Graves Wilson in the US was published in 1973. The book summarized information on the causes of malformations in newborns and aimed to acquaint policy makers with Wilson's suggestions for predicting the risks of environmental causes of birth defects, called teratogens. Wilson also provided six principles for researching teratogens, a framework revised from his 1959 article Experimental Studies on Congenital Malformations. The book has ten chapters.

Created 2014-06-21

Last modified 2 years 9 months ago

Format: Articles

The Origin of Species: "Chapter Thirteen: Mutual Affinities of Organic Beings: Morphology: Embryology: Rudimentary Organs" (1859), by Charles R. Darwin

By M. Elizabeth Barnes

Mutual Affinities of Organic Beings: Morphology: Embryology: Rudimentary Organs is the thirteenth chapter of Charles Darwin's book The Origin of Species, first published in England in 1859. The book details part of Darwin's argument for the common ancestry of life and natural selection as the cause of speciation. In this chapter, Darwin summarizes the evidence for evolution by connecting observations of development in organisms to the processes of natural selection.

Created 2014-07-11

Last modified 2 years 8 months ago

Format: Articles

"The Role of Maternal Mitochondria during Oogenesis, Fertilization and Embryogenesis" (2002), by James M. Cummins

By Dorothy R. Haskett

James M Cummins published 'The Role of Maternal Mitochondria during Oogenesis, Fertilization and Embryogenesis' 30 January 2002 in Reproductive BioMedicine Online. In the article, Cummins examines the role of the energy producing cytoplasmic particles, or organelles called mitochondria. Humans inherit mitochondria from their mothers, and mechanisms have evolved to eliminate sperm mitochondria in early embryonic development. Mitochondria contain their own DNA (mtDNA) separate from nuclear DNA (nDNA).

Created 2014-09-19

Last modified 2 years 6 months ago

Format: Articles

The Report of the Committee of Inquiry into Human Fertilisation and Embryology (1984), by Mary Warnock and the Committee of Inquiry into Human Fertilisation and Embryology

By LaTourelle, Jonathon J.

The Report of the Committee of Inquiry
into Human Fertilisation and Embryology, commonly called the Warnock
Report after the chair of the committee Mary Warnock, is the 1984
publication of a UK governmental inquiry into the social impacts of
infertility treatment and embryological research. The birth of Louise
Brown in 1978 in Oldham, UK, sparked debate about reproductive and
embryological technologies. Brown was conceived through in vitro
fertilization (IVF), a process of fertilization that occurs outside of

Created 2014-10-02

Last modified 2 years 4 months ago

Format: Articles

"Mitochondrial DNA and Human Evolution" (1987), by Rebecca Louise Cann, Mark Stoneking, and Allan Charles Wilson

By Dorothy R. Haskett

In 1987 Rebecca Louise Cann, Mark Stoneking, and Allan Charles Wilson published Mitochondrial DNA and Human Evolution in the journal Nature. The authors compared mitochondrial DNA from different human populations worldwide, and from those comparisons they argued that all human populations had a common ancestor in Africa around 200,000 years ago. Mitochondria DNA (mtDNA) is a small circular genome found in the subcellular organelles, called mitochondria.

Created 2014-10-10

Last modified 2 years 5 months ago

Format: Articles

Ontogeny and Phylogeny (1977), by Stephen Jay Gould

By M. Elizabeth Barnes

Ontogeny and Phylogeny is a book published in 1977, in which the author Stephen J. Gould, who worked in the US, tells a history of the theory of recapitulation. A theory of recapitulation aims to explain the relationship between the embryonic development of an organism (ontogeny) and the evolution of that organism's species (phylogeny). Although there are several variations of recapitulationist theories, most claim that during embryonic development an organism repeats the adult stages of organisms from those species in it's evolutionary history.

Created 2014-10-21

Last modified 2 years 5 months ago

Format: Articles

"The Origin and Behavior of Mutable Loci in Maize" (1950), by Barbara McClintock

By Federica Turriziani-Colonna

The Origin and Behavior of Mutable Loci in Maize, by Barbara McClintock, was published in 1950 in the Proceedings of the National Academy of Sciences of the United States of America. McClintock worked at the Cold Spring Harbor Laboratory in Laurel Hollow, New York, at the time of the publication, and describes her discovery of transposable elements in the genome of corn (Zea mays). Transposable elements, sometimes called transposons or jumping genes, are pieces of the chromosome capable of physically changing positions along the chromosome.

Created 2014-10-24

Last modified 2 years 4 months ago

Format: Articles

"Evolution and Tinkering" (1977), by Francois Jacob

By Valerie Racine

In his essay Evolution and Tinkering, published in
Science in 1977, Francois Jacob argued that a common analogy
between the process of evolution by natural selection and the
methods of engineering is problematic. Instead, he proposed to
describe the process of evolution with the concept of
bricolage (tinkering). In this essay, Jacob did not deny the
importance of the mechanism of natural selection in shaping complex
adaptations. Instead, he maintained that the cumulative effects of

Created 2014-10-24

Last modified 2 years 5 months ago

Format: Articles

"Hybrids and Chimeras: A Consultation on the Ethical and Social Implications of Creating Human/Animal Embryos in Research" (2007), by the HFEA

By Sarah Taddeo, Jason S. Robert

To educate its citizens about research into chimeras made from human and non-human animal cells, the United Kingdom's Human Fertilisation Embryology Authority published the consultation piece Hybrids and Chimeras: A Consultation on the Ethical and Social Implications of Creating Human/Animal Embryos in Research, in 2007.

Created 2014-11-04

Last modified 2 years 4 months ago

Format: Articles

"The Spandrels of San Marco and the Panglossian Paradigm: A Critique of the Adaptationist Programme" (1979), by Stephen J. Gould and Richard C. Lewontin

By M. Elizabeth Barnes

The Spandrels of San Marco and the Panglossian Paradigm:
A Critique of the Adaptationist Programme, hereafter called
The Spandrels, is an article written by Stephen J. Gould and
Richard C. Lewontin published in the Proceedings of the Royal
Society of London in 1979. The paper emphasizes issues with
what the two authors call adaptationism or the adaptationist
programme as a framework to explain how species and traits evolved. The paper
is one in a series of works in which Gould emphasized the

Created 2014-11-14

Last modified 2 years 4 months ago

Format: Articles

"Hybrids and Chimeras: A report on the findings of the consultation" by the Human Fertilisation and Embryology Authority in October, 2007

By Sarah Taddeo, Jason S. Robert

In 2007, the Human Fertilisation and Embryology Authority in London, UK, published Hybrids and Chimeras: A Report on the Findings of the Consultation, which summarized a public debate about research on, and suggested policy for, human animal chimeras. The HFEA formulated the report after conducting a series of surveys and debates from earlier in 2007. The HFEA issued a statement in September 2007, followed by an official report published on 1 October 2007. Their report on human-animal chimeras set a worldwide precedent for discussions of the ethical use of those embryos in labs.

Created 2014-11-22

Last modified 2 years 4 months ago

Format: Articles

The Germ-Plasm: a Theory of Heredity (1893), by August Weismann

By Yawen Zou

Friedrich Leopold August Weismann published Das
Keimplasma: eine Theorie der Vererbung (The Germ-Plasm: a
Theory of Heredity, hereafter The Germ-Plasm) while
working at the University of Freiburg in Freiburg, Germany in 1892.
William N. Parker, a professor in the University College of South
Wales and Monmouthshire in Cardiff, UK, translated The
Germ-Plasm into English in 1893. In The Germ-Plasm,
Weismann proposed a theory of heredity based on the concept of the

Created 2015-01-26

Last modified 2 years 1 month ago

Format: Articles

The Inheritance of Acquired Characteristics (1924), by Paul Kammerer

By Federica Turriziani Colonna

The Inheritance of Acquired Characteristics is a book published in 1924, written by Paul Kammerer, who studied developmental biology in Vienna, Austria, in the early twentieth century. The Inheritance of Acquired Characteristics summarizes Kammerer's experiments, and explains their significance. In his book, Kammerer aims to explain how offspring inherit traits from their parents. Some scholars criticized Kammerer's reports and interpretations, arguing that they were inaccurate and misleading, while others supported Kammerer's work.

Created 2015-03-31

Last modified 1 year 11 months ago

Format: Articles

The Cell in Development and Inheritance (1900), by Edmund Beecher Wilson

By Abhinav Mishra, Jane Maienschein

The Cell in Development and Inheritance, by Edmund Beecher Wilson, provided a textbook introduction to cell biology for generations of biologists in the twentieth century. In his book, Wilson integrated information about development, inheritance, chromosomes, organelles, and the structure and functions of cells. First published in 1896, the book started with 371 pages, grew to 483 pages in the second edition that appeared in 1900, and expanded to 1,231 pages by the third and final edition in 1925.

Created 2015-06-18

Last modified 1 year 9 months ago

Format: Articles

Eugenical Sterilization in the United States (1922), by Harry H. Laughlin

By Rachel Gur-Arie

Eugenical Sterilization in the United States is a 1922 book in which author Harry H. Laughlin argues for the necessity of compulsory sterilization in the United States based on the principles of eugenics. The eugenics movement of the early twentieth century in the US focused on altering the genetic makeup of the US population by regulating immigration and sterilization, and by discouraging interracial procreation, then called miscegenation.

Created 2015-08-12

Last modified 1 year 7 months ago

Format: Articles

People's Padre: An Autobiography (1954), by Emmett McLoughlin

By Claudia Nunez-Eddy

Emmett McLoughlin wrote People's Padre: An Autobiography, based on his experiences as a Roman Catholic priest advocating for the health of people in Arizona. The Beacon Press in Boston, Massachusetts, published the autobiography in 1954. McLoughlin was a Franciscan Order Roman Catholic priest who advocated for public housing and healthcare for the poor and for minority groups in Phoenix, Arizona, during the mid twentieth century. The autobiography recounts McLoughlin's efforts in founding several community initiatives throughout Phoenix, including the St.

Created 2016-11-08

Last modified 4 months 2 weeks ago

Format: Articles

De ovi mammalium et hominis genesi (1827), by Karl Ernst von Baer

By Federica Turriziani Colonna

De ovi mammalium et hominis genesi (On the Genesis of the Ovum of Mammals and of Men) is an 1827 pamphlet by Karl Ernst von Baer about the anatomical observation and description of the egg (ovum) of mammals, like dogs and humans. The pamphlet detailed evidence for the existence of the ovum at the beginning of the developmental process in mammals.

Created 2017-02-09

Last modified 11 hours 54 min ago

Format: Article

Gattaca (1997)

By Grace Kim

Gattaca is a 1997 science fiction film produced in the US that depicts a future society that uses reproductive technology and genetic engineering in order to produce genetically enhanced human beings. By selectively choosing certain genes, scientists and physicians ensure that individuals born using reproductive technologies have desirable physical and psychological traits and prevent undesirable traits.

Created 2017-02-09

Last modified 11 hours 54 min ago

Format: Article

“Elective Induction of Labor” (1955), by Edward Bishop

By Carolina J. Abboud

In 1955, obstetrician Edward Bishop, a physician specializing in childbirth, published the article “Elective Induction of Labor,” in which he proposed the best conditions for pregnant women to elect to induce, or begin, labor. Elective induction of labor requires an obstetrician to administer a drug to help a pregnant woman to start her contractions, and to rupture the fluid-filled sac surrounding the fetus called the amniotic sac.

Created 2017-02-16

Last modified 11 hours 53 min ago

Format: Article

“Diethylstilbestrol in the Prevention and Treatment of Complications of Pregnancy” (1948), by Olive Watkins Smith

By Alexis Abboud

In 1948, Olive Watkins Smith published 'Diethylstilbestrol in the Prevention and Treatment of Complications of Pregnancy' in the American Journal of Obstetrics and Gynecology. In 632 women treated with diethylstilbestrol, Smith demonstrated that the drug stimulated the production of progesterone, a hormone that regulates the uterine condition during pregnancy.

Created 2017-02-21

Last modified 11 hours 52 min ago

Format: Article

“Pelvic Scoring for Elective Induction” (1964), by Edward Bishop

By Carolina J. Abboud

In the 1964 article, “Pelvic Scoring for Elective Induction,” obstetrician Edward Bishop describes his method to determine whether a doctor should induce labor, or artificially start the birthing process, in a pregnant woman. Aside from medical emergencies, a woman can elect to induce labor to choose when she gives birth and have a shorter than normal labor. The 1964 publication followed an earlier article by Bishop, also about elective induction.

Created 2017-02-23

Last modified 11 hours 52 min ago

Format: Article

"'Doing the Month': Confinement and Convalescence of Chinese Women After Childbirth" (1978), by Barbara L.K. Pillsbury

By Cecilia Chou

In 1978 Social Science and Medicine published Barbara L.K. Pillsbury's article, 'Doing the Month': Confinement and Convalescence of Chinese Women After Childbirth, which summarized the results of Pillsbury's study on Chinese childbirth customs. Pillsbury, a professor of cultural anthropology at San Diego State University in San Diego, California, conducted over eighty interviews with people in Taiwan and China, including civilians, herbalists, and physicians over a four-month period in 1975.

Created 2017-03-16

Last modified 11 hours 47 min ago

Format: Article

"The Environment and Disease: Association or Causation?" (1965), by Austin Bradford Hill

By Carolina J. Abboud

In 1965, Austin Bradford Hill published the article “The Environment and Disease: Association or Causation?” in the Proceedings of the Royal Society of Medicine. In the article, Hill describes nine criteria to determine if an environmental factor, especially a condition or hazard in a work environment, causes an illness. The article arose from an inaugural presidential address Hill gave at the 1965 meeting of the Section of Occupational Medicine of the Royal Society of Medicine in London, England.

Created 2017-03-23

Last modified 10 hours 56 min ago

Format: Articles

Infant Mortality: Results of a Field Study in Johnstown, PA., Based on Births in One Calendar Year (1915), by Emma Duke

By Katherine Madgett

The book Infant Mortality: Results of a Field Study in Johnstown, PA., Based on Births in One Calendar Year (1915), written by Emma Duke, detailed one of the first infant mortality field studies conducted by the US Children's Bureau. In the study, Duke and her colleagues collected information about over one thousand infants in the city of Johnstown, Pennsylvania. They used that information, along with interviews conducted with the families of the infants, to identify factors that affected infant mortality rates in the community.

Created 2017-03-23

Last modified 11 hours 46 min ago

Format: Article

“An Extended Family with a Dominantly Inherited Speech Disorder” (1990), by Jane A. Hurst et al.

By Kat Fowler

In 1990, researcher Jane Hurst and her colleagues published “An Extended Family With a Dominantly Inherited Speech Disorder,” in which they proposed that a single gene was responsible for a language disorder across three generations of a family. Affected individuals of the family, called the KE family, had difficulty producing, expressing and comprehending speech. Hurst and her team studied the KE family and the disorder at the Department of Clinical Genetics at the Great Ormond Street Hospital for Children in London, England.

Created 2017-03-23

Last modified 11 hours 46 min ago

Format: Article

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