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Estrogen plays a key role in the regulation of gene transcription. This is accomplished by its ability to act as a ligand and to bind to specific…
DiethylstilbestrolEstrogenHuman DevelopmentPublished in 1971, Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, by Arthurs L.…
LiteratureDiethylstilbestrolAdenocarcinomaCancerEstrogenIn the early 1920s, researchers Edgar Allen and Edward Adelbert Doisy conducted an experiment that demonstrated that ovarian follicles, which produce…
OvariesCorpus LuteumEndometriumEstrogenHormones, SexThe article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformationsEugen Steinach researched sex hormones and their effects on mammals in the late nineteenth and early twentieth centuries in Europe. He experimented…
Hormones, SexGenerative organsGenital OrgansGonadal Steroid HormonesTesticular HormonesEdgar Allen identified and outlined the role of female sex hormones and discovered estrogen in the early 1900s in the US. In 1923, Allen, through his…
EstrogenHormones, SexOogenesisEstrusMenstrual CycleDiethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant…
DiethylstilbestrolDiethylstilbestrol--Side effectsDiethylstilbestrol--CarcinogenicityPregnancyEstrogenEstrogen is the primary sex hormone in women and it functions during the reproductive menstrual cycle. Women have three major types of estrogen:…
Menstrual CycleOral contraceptivesEstrogenEstradiolEstroneSindell v. Abbott Laboratories was a 1980 California case that established the doctrine of market share liability for personal injury cases. For such…
LawDiethylstilbestrolMiscarriagePregnancy--ComplicationsPregnancyIn the early twentieth century US, Jean Paul Pratt and Edgar Allen conducted clinical experiments on women who had abnormal menstrual cycles. During…
EstrogenEndocrinologyDoisy, Edward Adelbert, 1893-1986MenstruationUterus