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Isotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogensTruman William Brophy developed a cleft palate surgical repair, later called the Brophy Operation, in the late nineteenth century US. The procedure…
Cleft PalateDental EducationAmerican Dental AssociationmalformationsBirth DefectsIn 1861, William John Little published, “On The Influence of Abnormal Parturition, Difficult Labors, Premature Birth, and Asphyxia Neonatorum, on the…
LiteratureBirth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticityFortunio Liceti studied natural philosophy and medicine in Italy during the first half of the seventeenth century. Liceti wrote greater than seventy…
TeratologyAbnormalities, HumanAnimals--AbnormalitiesEmbryologyPathologyIn 2015, the Public Broadcasting Service, or PBS, released a three-part documentary series, Twice Born–Stories from the Special Delivery Unit,…
LiteratureFetus--SurgerySpina BifidaTeratomaObstetrics--SurgeryWilliam John Little was one of the first orthopedic surgeons to research congenital malformations and their causes in the nineteenth century and…
Birth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticitySpasticityIn March 1996, the National Academy of Sciences of the United States released 'Veterans and Agent Orange Update 1996: Summary and Research Highlights…
LiteratureAgent OrangeHerbicidesSpina BifidaVeterans AdministrationVirginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women’s pain during childbirth, in the US in the mid-…
Apgar, Virginia, 1909-1974Apgar ScorePregnancyObstetricsChildbirthIn 1988, the US Centers for Disease Control published 'Health Status of Vietnam Veterans III. Reproductive Outcomes and Child Health,' which…
LiteratureAgent OrangeHerbicidesSpina BifidaVeterans Administration