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George Wells Beadle and Edward Lawrie Tatum's 1941 article Genetic Control of Biochemical Reactions in Neurospora detailed their experiments on how…
GenesGeneticsExperimentsNeurosporaMolecular BiologyDavid Wildt's cheetah (Acinonyx jubatus) research from 1978-1983 became the foundation for the use of embryological techniques in endangered species…
Endangered SpeciesExperimentsCatsFertilityIn 1913, Alfred Henry Sturtevant published the results of experiments in which he showed how genes are arranged along a chromosome. Sturtevant…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutationPaul M. Brakefield and his research team in Leiden, the Netherlands, examined the development, plasticity, and evolution of butterfly eyespot…
ButterfliesDevelopmental BiologyPhenotypic plasticityGenotype-environment interactionEvolutionary developmental biologyThe paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMiceIn 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidyShoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial DiseasesIn the 1990s, researchers working at the Roslin Institute in Edinburgh, Scotland, performed cloning experiments in collaboration with PPL…
CloningChristmas FactorBlood coagulation factor IXRoslin InstituteWilmut, IanIn the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNAAdvanced Cell Technology (ACT), a stem cell biotechnology company in Worcester, Massachusetts, showed the potential for cloning to contribute to…
Cell nuclei--TransplantationCloningGaurAdvanced Cell Technology (Firm)Embryos