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James Graves Wilson's six principles of teratology, published in 1959, guide research on teratogenic agents and their effects on developing organisms…
TeratologyAbnormalities, HumanCongenital AbnormalitiesBirth DefectsCongenital DefectsVitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agentsMichael R. Harrison worked as a pediatric surgeon in the US throughout the late-twentieth century and performed many fetal surgeries, including one…
Birth DefectsAbnormalities, HumanPediatric surgeonsMyelomeningoceleSpinal DysraphismThalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomideThe article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformationsThe March of Dimes Foundation, or the March of Dimes, is a non-profit organization headquartered in Arlington, Virginia, focused on the health of…
OrganizationsPoliomyelitisInfantile ParalysisPolioBirth DefectsIn 1861, William John Little published, “On The Influence of Abnormal Parturition, Difficult Labors, Premature Birth, and Asphyxia Neonatorum, on the…
LiteratureBirth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticityWilliam John Little was one of the first orthopedic surgeons to research congenital malformations and their causes in the nineteenth century and…
Birth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticitySpasticityIn June 2017, the Iowa Supreme Court decided the case Plowman v. Fort Madison Community Hospital, or Plowman v. FMCH, and ruled that women who gave…
LawWrongful lifeWrongful BirthAbnormalities, HumanIowa