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In the early 1960s, John W. Saunders Jr., Mary T. Gasseling, and Lilyan C. Saunders in the US investigated how cells die in the developing limbs of…
Cell DeathChickens--EmbryosApoptosisExperimentsAn important question throughout the history of embryology is whether the formation of a biological structure is predetermined or shaped by its…
Hamburger, Viktor, 1900-2001ExperimentsNervous SystemCell DeathGerman embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicksRichard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormonesThe biomedical accomplishment of human in vitro fertilization and embryo transfer (IVF-ET) took years to become the successful technique that…
ReproductionExperimentsFertilizationOn 10 March 1988, China's first baby conceived through human in vitro fertilization (IVF) and embryo transfer (ET), commonly referred to as a test-…
ReproductionExperimentsFertility'On the Permanent Life of Tissues outside of the Organism' reports Alexis Carrel's 1912 experiments on the maintenance of tissue in culture media. At…
Tissue cultureStem CellsStem cells--ResearchEmbryologyGerm CellsIn an effort to develop tissue culture techniques for long-term tissue cultivation, French surgeon and biologist Alexis Carrel, and his associates,…
Carrel, Alexis, 1873-1944Tissue cultureCellsGerm CellsEmbryosThe p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell DeathRobert Geoffrey Edwards, a British developmental biologist at University of Cambridge, began exploring human in vitro fertilization (IVF) as a way to…
Fertilization in VitroExperimentsReproductionFertilizationOocytes