Richard Doll (1912–2005)

Richard Doll (1912–2005)Richard Doll was an epidemiologist and public figure in the twentieth and early twenty-first centuries. Working primarily at the University of Oxford, in Oxford, England, Doll established a definitive correlation between cigarette smoking and lung cancer. Furthermore, Doll’s work helped legitimize epidemiology as a scientific discipline. Doll’s research also helped establish modern guidelines for oncological studies, as well as for contemporary and future research on the effect of smoking on pregnancy and fetal development. In addition to studying the health effects of smoking, Doll also studied cervical cancer and contraceptives.

"Predictors of Postpartum Depression: An Update” (2001), by Cheryl Tatano Beck

“Predictors of Postpartum Depression: An Update” (2001), by Cheryl Tatano Beck In her 2001 paper “Predictors of Postpartum Depression: An Update,” researcher Cheryl Tatano Beck presents the most common risk factors associated with postpartum depression in women. Postpartum depression occurs when women experience symptoms such as tearfulness, extreme mood changes, and loss of appetite for a lengthened period after giving birth. At the University of Connecticut in Storrs, Connecticut, nursing professor Beck updated a previous study of hers by analyzing literature about postpartum depression published in the 1990s. Beck found four predictors of postpartum depression that she had not included in her previous study. “Predictors of Postpartum Depression: An Update” presents risk factors that healthcare professionals can use to predict

Oliver Allison Ryder III (1946– )

Oliver Allison Ryder III (1946– )Oliver Allison Ryder studied chromosomal evolution and endangered species in efforts for wildlife conservation and preservation at the San Diego Zoo in San Diego, California. Throughout his career, Ryder studied breeding patterns of endangered species. He collected and preserved cells, tissues, and DNA from endangered and extinct species to store in the San Diego Frozen Zoo, a center for genetic research and development in San Diego, California. Ryder and his team also sequenced vertebrate genomes under the Genome 10k initiative, a collaborative international program aiming to analyze the complete genomes of over ten thousand species of vertebrate. Ryder’s research has helped preserve species, restore diminished populations of wildlife, and protect biodiversity.

Torsten Wiesel (1924– )

Torsten Wiesel (1924– )Torsten Nils Wiesel studied visual information processing and development in the US during the twentieth century. He performed multiple experiments on cats in which he sewed one of their eyes shut and monitored the response of the cat’s visual system after opening the sutured eye. For his work on visual processing, Wiesel received the Nobel Prize in Physiology or Medicine in 1981 along with David Hubel and Roger Sperry.

Shoukhrat Mitalipov and Masahito Tachibana's Mitochondrial Gene Replacement Therapy Technique

Shoukhrat Mitalipov and Masahito Tachibana's Mitochondrial Gene Replacement Therapy TechniqueIn 2009, Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers developed the technology of mitochondrial gene replacement therapy to prevent the transmission of a mitochondrial disease from mother to offspring in primates. Mitochondria contain some of the body's genetic material, called mitochondrial DNA. Occasionally, the mitochondrial DNA possesses mutations. Mitalipov and Tachibana, researchers at the Oregon National Primate Research Center in Beaverton, Oregon, developed a technique to remove the nucleus of the mother and place it in a donor oocyte, or immature egg cell, with healthy

Stafford Leak Warren (1896–1981)

Stafford Leak Warren (1896–1981)Stafford Leak Warren studied nuclear medicine in the United States during the twentieth century. He used radiation to make images of the body for diagnosis or treatment and developed the mammogram, a breast imaging technique that uses low-energy X-rays to produce an image of breasts. Mammograms allow doctors to diagnose breast cancer in its early and most treatable stages. Warren was also a medical advisor to the Manhattan Project, the US government’s program to develop an atomic bomb during World War II, and he was responsible for the health and safety aspects of the Trinity Test, the first atomic bomb test in the US. Warren’s invention of the mammogram has allowed physicians to diagnose breast cancer in women during its most treatable stages, preventing deaths due to breast

Neonatal Respiratory Distress Syndrome and Its Treatment with Artificial Surfactant

Neonatal Respiratory Distress Syndrome and Its Treatment with Artificial SurfactantNeonatal respiratory distress syndrome, previously called hyaline membrane disease, is a respiratory disease affecting premature newborns. Neonatal respiratory distress syndrome involves shallow breathing, pauses between breaths that last a few seconds, or apnea, and a bluish tinge to the infant’s skin. The syndrome occurs when microscopic sacs called alveoli in infant lungs do not produce surfactant, a liquid that coats the inside of the lungs and helps them inflate during breathing. Respiratory distress syndrome is the leading cause of death among premature

Mary-Claire King (1946– )

Mary-Claire King (1946– )Mary-Claire King studied genetics in the US in the twenty-first century. King identified two genes associated with the occurrence of breast cancer, breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2). King showed that mutated BRCA1 and BRCA2 genes cause two types of reproductive cancer, breast and ovarian cancer. Because of King’s discovery, doctors can screen women for the inheritance of mutated BRCA1 and BRCA2 genes to evaluate their risks for breast and ovarian cancer. King also demonstrated the

Ann Trow (Madame Restell) (1812–1878)

Ann Trow (Madame Restell) (1812–1878)Self-proclaimed female physician Ann Trow was a women’s reproductive health specialist as well as an abortion provider in New York City, New York during the mid 1800s. Although she had no formal medical training or background, Trow provided women with healthcare and abortions under the alias Madame Restell. Restell gained attention across the United States for her career as a professional abortionist during a time when abortions were highly regulated and punishable with imprisonment. Restell was tried numerous times for carrying out abortions. She never confessed to any crimes, but she was convicted on several occasions. Her services as a business woman, medicine producer, abortion provider, boarding

Light Therapy for Neonatal Jaundice

Light Therapy for Neonatal Jaundice Light therapy, also called phototherapy, exposes infants with jaundice, a yellowing of the skin and eyes, to artificial or natural light to break down the buildup of bilirubin pigment in the blood. Bilirubin is an orange to red pigment produced when red blood cells break down, which causes infants to turn into a yellowish color. Small amounts of bilirubin in the blood are normal, but when there is an accumulation of excess bilirubin pigment, the body deposits the excess bilirubin in the layer of fat beneath the skin. That accumulation of bilirubin causes the skin and the white areas of the eye to appear yellowed, a common symptom of jaundice. Buildup of bilirubin typically occurs when the immature liver of a newborn